SLEEP, LYMPHOKINES, HORMONES, IMMUNITY IN PSYCHIATRIC PATIENTS

精神病患者的睡眠、淋巴因子、激素、免疫力

• 批准号: 6117918
• 负责人: Michael R Irwin
• 金额: $ 1.46万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN DIEGO
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-12-01 至 1999-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6117918
• 关键词: behavioral /social science research tag; catecholamines; clinical research; electroencephalography; human subject; lymphokines; mental disorders; neuroendocrine system; neurohormones; neurotransmitters; protein biosynthesis; psychoneuroimmunology; sleep; sleep deprivation; sleep disorders; sympathetic nervous system; wakefulness

Establish the relationship between EEG, sleep, sympathetic tone and immune function, characterize the nocturnal secretary profile of lymphokines, neuroendocrine hormones and neurotransmitters, examine catecholamines in psychaitric patients with sleep disturbance, and test the link between sleep, neuroendocrine and sympathetic measures and immunologic responses using partial sleep deprivation.

建立脑电图、睡眠、交感神经张力和免疫功能之间的关系，描述淋巴因子、神经内分泌激素和神经递质的夜间分泌特征，检测有睡眠障碍的精神病患者的儿茶酚胺，并使用部分睡眠剥夺测试睡眠、神经内分泌和交感神经测量与免疫反应之间的联系。