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PK & RISK FACTORS FOR RELAPSE AMONG HIV+ & HIV- IN RIFAPENTINE TRIAL

PK & RISK FACTORS FOR RELAPSE AMONG HIV+ & HIV- IN RIFAPENTINE TRIAL
PK
批准号：
6265159
负责人：
ANTONINO CATANZARO
金额：
$1.15万
依托单位：
UNIVERSITY OF CALIFORNIA, SAN DIEGO
依托单位国家：
美国
项目类别：
财政年份：
1998
资助国家：
美国
项目状态：
已结题
起止时间：
1998-12-01 至 1999-11-30
来源：
https://reporter.nih.gov/project-details/6265159
关键词：
AIDS therapy HIV infections antiAIDS agent blood chemistry clinical research disease /disorder proneness /risk drug screening /evaluation human subject human therapy evaluation microorganism disease chemotherapy neoplasm /cancer relapse /recurrence pharmacokinetics rifamycins urinalysis

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中文摘要
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英文摘要
Study INH and rifamycin pharmacokinetics in HIV+ participants in the Rifapentine Clinical Trial, define INH acetylator status in 2 subgroups of participants in the Rifapentine trial (HIV+ participants and all participants who experienced failure or relapse), ascertain the degree of bioavailability of INH and of rifapentine or rifampin to same subgroups of participants, and compare the use of urine and blood for pharmacokinetic screening in participants in Rifapentine Clinical Trial.
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