SOMATOTROPIN TREATMENT OF GROWTH RETARDATION IN IDIOPATHIC SHORT CHILDREN

生长激素治疗特发性矮小儿童生长迟缓

• 批准号: 6118368
• 负责人: BARBARA M LIPPE
• 金额: $ 2.51万
• 依托单位: UNIVERSITY OF CALIFORNIA LOS ANGELES
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/6118368
• 关键词: body height; child (0-11); child physical development; clinical research; clinical trials; hormone therapy; human subject; human therapy evaluation; longitudinal human study; pediatric pharmacology; postnatal growth disorder; somatotropin

A 3-year, randomized, controlled multicenter study of the effect of growth hormone (GH) treatment upon short, normal children to treat a possibly impaired endogenous GH secretion. Results will help to show if GH treatment of normal, short children cann accelerate their short- term growth velocity, ncrease their ultimate height prediction, or both.

一项为期3年的随机对照多中心研究， 生长激素（GH）治疗后，短，正常的儿童，以治疗 内源性生长激素分泌可能受损。 结果将有助于显示 如果生长激素治疗正常矮小儿童， 长期增长速度，增加他们的最终高度预测，或两者兼而有之。