PRINCIPAL NIH RESEARCH RESOURCE X RAY BEAMLINE AT NSLS: WIGGLER BEAMLINE X25

几年来，X25可以说是最受欢迎的 在美国的光束线。事实上，大分子 结晶学测量最近在竞争中表现出色 进入这个设施说明了可能的结果的重要性， 以及实验者所做准备的质量。然而， 部分原因是赢得光束线时间的用户已经 来自美国最有经验的团体，部分原因是 可用于教学的人员太少，而且 在游客的监督下，光束线已经运行在一个相对 PX的原始模式：不符合标准的检测器，软件不 不仅仅是简单的操作，经验丰富的人几乎没有帮助 结晶学家在操作方面的初步培训以外 光束线。因此，我们将着手进行这项技术开发 建立设备、软件和方法的项目，不仅 将增强我们进行不可能的测量的能力 NSLS蘸了一颗棕榈油，也绝对会做出最大 有效利用这一宝贵资源。在某种程度上，项目1。 1和1.2是其中的一部分--软件和硬件的开发。 X25成为所有这些开发必须实现的焦点 共同实现最高目标，解决最困难的问题 生物问题。

For several years X25 arguably has been the most sought-after beamline in the United States. The fact that macromolecular crystallographic measurements have competed so well recently for access to this facility speaks to the importance of the likely result, and the quality of preparations made by the experimenters. However, partially because the users who win time on the beamline have been from the most experienced groups in the U.S., and partially because there has been too little personnel available for teaching and supervision of visitors, the beamline has run in a relatively primitive mode for PX: substandard detectors, software that does not go beyond simple operations, and little assistance from experienced crystallographers beyond initial training in operation of the beamline. Therefore, we will embark on this technological development project to establish apparatus, software, and methods that not only will enhance our ability to make measurements that are impossible on NSLS dip ole bearrilines, but also will make absolutely the most efficient use of this precious resource. To some extent, projects 1. 1 and 1.2 are a part of this - development of software and hardware. X25 becomes the focus point where all of these developments must come together to achieve the highest goals and to solve the most difficult biological problems.