STRESS AND AGING; MECHANISMS, MODELS AND INTERVENTIONS

第29届美国老龄化协会年会将于2000年6月2日至5日在波士顿Tremont酒店和位于马萨诸塞州波士顿塔夫茨大学的美国农业部（USDA）人类营养衰老研究中心举行，该提案要求为出席会议的演讲者提供一年的旅费和住宿费支持。本次会议的重点是“衰老中的压力：机制、模型和干预”。重点关注压力与衰老和与年龄有关的疾病的关系，将包括氧化和环境压力的各个方面，专题讨论会针对潜在机制、动物和体外模型，以及旨在改善与年龄有关的压力的负面影响的干预措施，例如热量限制和营养方案。这些主题包含了生物老年学的不同领域，这些领域在研究和公共社区中受到越来越多的关注，因此将吸引具有不同背景和对衰老有共同兴趣的科学家。会议包括六个专题讨论会：线粒体参与氧化应激和衰老的机制；氧化应激对细胞的影响；氧化应激与神经变性；抗氧化剂及干预措施；生理应激的综合反应；六、胁迫响应的分子表征。除了这六场专题讨论会，6月2日还将举行一场题为“衰老研究中的DNA微阵列”的会前研讨会。研讨会将为成熟的研究人员和学生提供一个机会，让他们了解这种令人兴奋的方法，重要的技术考虑以及将其应用于许多生物老年学领域的可能性。最后，塔夫茨大学人类营养研究中心将于6月5日主办一场题为“饮食干预衰老和年龄相关疾病”的研讨会。

The proposal requests the single-year support of travel and lodging expenses for speakers at the 29th annual American Aging Association (AGE) meeting being held June 2 - 5, 2000, at the Tremont Boston hotel and the Jean Mayer United States Department of Agriculture (USDA) Human Nutrition Research Center on Aging at Tufts University in Boston, Massachusetts. The emphasis of this meeting is "Stress in Aging: Mechanisms, Models and Interventions." The focus on the involvement of stress in aging and age-related diseases will include aspects of both oxidative and environmental stresses with symposia directed at potential mechanisms, animal and in vitro models, and interventions aimed at ameliorating the negative impact of age-related stresses, e.g., caloric restriction and nutritional regimens. These topics incorporate diverse areas of biogerontology which are receiving increasing attention in the research and public communities and will, therefore, attract scientists with divergent backgrounds and a common interest in aging. The meeting consists of six symposia: I Mechanisms of Mitochondrial Involvement in Oxidative Stress and Aging; II Cellular Impact of Oxidative Stress; III Oxidative Stress and Neurodegeneration; IV Antioxidants and Interventions; V Integrated Responses to Physiological Stress; VI Molecular Characterization of the Stress Response. In addition to the six symposia, there will be a preconference workshop on June 2nd entitled, "DNA Microarrays in the Study of Aging." The workshop will provide an opportunity for both established researchers and students to learn about this exciting methodology, important technical considerations and the possibilities for its application to many areas of biogerontology. Lastly, a symposium entitled, "Dietary Interventions in Aging and Age-Associated Disease" will be sponsored by the Human Nutrition Research Center on Aging at Tufts University on June 5th.