VENTRICULAR FUNCTION DURING CARDIAC SURGERY

心脏手术期间的心室功能

• 批准号: 6125935
• 负责人: HENRY Michael SPOTNITZ
• 金额: $ 29.49万
• 依托单位: COLUMBIA UNIVERSITY HEALTH SCIENCES
• 依托单位国家: 美国
• 财政年份: 1992
• 资助国家: 美国
• 起止时间: 1992-05-01 至 2000-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6125935
• 关键词: adult human (21+); angiocardioultrasonography; bioimaging /biomedical imaging; blood flow measurement; clinical research; coronary bypass; diagnosis design /evaluation; diagnosis quality /standard; echocardiography; heart catheterization; heart circulation; heart function; heart surgery; heart ventricle; human subject; intracardiac volume; longitudinal human study; newborn human (0-6 weeks); patient care; pediatrics; postoperative state; swine

DESCRIPTION: (Adapted from investigator's abstract) In this revised application the investigators wish to pursue two main goals: expand Q2-DE to the pediatric population of patients and establish the utility of the conductance catheter method for measurement of ventricular volumes in adult patients. They also wish to study intra-operatively and at 2 and 6 weeks and 6 months postoperatively both adult and pediatric patients that had open heart surgery for a variety of valvular congenital and ischemic lesions. With the development of reliable methods to measure ventricular volume, the PI wishes to combine these data with pressure measurements to assess myocardial mechanics and edema during operation and up to six months afterwards.

描述：（改编自研究者摘要）在本修订版中 研究人员希望追求两个主要目标：扩大Q2-DE 儿童患者群体，并建立 电导导管法测定成人心室容积 患者 他们还希望在术中以及第2周和第6周进行研究 术后6个月， 心脏手术治疗各种瓣膜先天性和缺血性病变。 随着心室容积测量方法的发展， PI希望将这些数据与压力测量值结合联合收割机，以评估 手术期间和长达6个月的心肌力学和水肿 事后