TRAINING IN INVESTIGATIVE AND MOLECULAR DERMATOLOGY

描述（来自申请）：本申请是1991年在凯斯西储大学（CWRU）成立的调查和分子皮肤病学培训计划的竞争性更新。该计划的主要目标是为高素质的年轻研究人员提供调查皮肤病学和皮肤生物学方面最先进的跨学科研究培训机会。合格的候选人包括医生（M.D.的）与至少两年的临床皮肤病学培训和基础科学家（博士）。的），拥有长达两年的博士后经验，两人都明确致力于研究性皮肤病学或基础皮肤生物学的学术生涯。为四个研究领域之一的学员开发个性化的职业建设计划，每个研究领域都与皮肤的生理学和病理学有关：免疫生物学，分子和细胞生物学，光皮肤学/光医学和皮肤药理学/致癌作用。每个研究员选择这四个培训轨道之一，这是由一个主任和一个共同主任和参与教师谁是国家和国际公认的领导人在该领域，谁有校外资助的研究计划，并在该学科公认的培训师监督。通过这一重点突出但互动的机制，学员将学习如何科学地处理皮肤生物学问题，并有机会获得现代研究方法和使用先进设备的经验。每个研究员都提供指导，设计和执行一套连贯的实验，解决特定的假设。两周一次的正式讨论强调伦理分析和结果的公布。除了实验室培训外，研究员还参加课程、讲习班、专题讨论会和数据介绍活动，并被要求在科学会议上介绍他们的工作，包括皮肤病研究学会年会。因此，培训是通过密集参与重点研究项目和通过会议/研讨会进行的，在这些会议/研讨会上进行基础科学研究以及将研究应用于临床问题。十七CWRU培训教师有一个优秀的培训记录，他们的凝聚力是由一个以研究为导向的皮肤科主席的领导加强。所有教师都是NIH资助的皮肤病研究中心的积极成员。CWRU的这个多学科中心为基础科学和临床部门之间的合作互动奠定了坚实的基础，并为考虑从事学术皮肤病学职业的年轻研究人员提供了理想的培训里程碑。

DESCRIPTION (from the application): This application is a competitive renewal of the Training Program in Investigative and Molecular Dermatology that was established in 1991 at Case Western Reserve University (CWRU). The major objective of this program is to provide highly qualified, young investigators with opportunities for state-of-the-art interdisciplinary research training in investigative dermatology and cutaneous biology. Eligible candidates include physicians (M.D.'s) with a minimum of two years of clinical dermatology training and basic scientists (Ph.D.'s) with up to two years of postdoctoral experience, both of whom have a definite commitment to an academic career in investigative dermatology or basic cutaneous biology. Individualized career building programs are developed for trainees in one of four research areas, each of which is related to the physiology and pathology of the skin: immunobiology, molecular and cellular biology, photodermatology/photomedicine, and skin pharmacology/carcinogenesis. Each fellow selects one of these four training tracks, which is supervised by a Director and a Co- Director and participating faculty members who are nationally and internationally recognized leaders in that field and who have extramurally funded research programs and are recognized trainers in that discipline. Through this focused, yet interactive mechanism, the trainees are taught how to scientifically approach problems in cutaneous biology and are given the opportunity to gain experience in modern research methodology and in the use of sophisticated equipment. Each fellow is provided guidance in the design and performance of a coherent set of experiments which addresses specific hypotheses. A biweekly formal discussion emphasizes the ethical analysis and publication of results. In addition to laboratory training, the fellows participate in courses, workshops, symposia and data presentation exercises and are required to present their work at scientific meetings including the annual meeting of the Society for Investigative Dermatology. Thus, training occurs through intensive participation in a focused research project and through conferences/seminars in which the basic science research, as well as the application of research to clinical problems are implemented. The seventeen CWRU training faculty have an excellent training record, and their cohesiveness is strengthened by the leadership of a research-oriented Dermatology Chairman. All faculty are active members of the NIH- funded Skin Diseases Research Center. This multidisciplinary Center at CWRU has created a strong foundation for cooperative interactions between basic science and clinical departments and provides an ideal training mileau for young investigators contemplating a career in academic dermatology.