ACADEMIC RHEUMATOLOGY AND CLINICAL IMMUNOLOGY

加州大学旧金山分校学术风湿学和临床免疫学培训计划的总体目标是为计划从事学术风湿学职业的拥有医学博士、医学博士或博士学位的合格个人提供生物医学研究和卫生服务研究方面的高级培训。该计划的一个主要目标是为受训者提供一个环境，使他们能够：(1)在选定的集中领域进行正式的教学课程工作；(2)学习如何深入研究科学问题；掌握最先进的研究技术；以及(4)理解什么是好的科学。过去，我们项目的培训利用了加州大学旧金山分校医学系风湿病科的资源：一个在莫菲特-隆大学医院，一个在旧金山综合医院，一个在旧金山A医学中心。这些部门在医学科学中发展最快的两个领域--免疫学和分子生物学中的生物医学研究，以及侧重于结果研究的卫生服务研究--具有特别的优势。这些优势领域是对基础科学最近前所未有的进步和国家在保健提供方面的重要变化作出反应的。在这次竞争性续签申请中，我们建议在两个关键领域进一步加强我们的计划。首先，我们建议包括对儿科风湿病博士后研究员的研究培训。近年来，加州大学旧金山分校建立了全国顶级的儿科风湿病学临床课程之一，这将有利于成人和儿科风湿病学的学员。正式整合研究项目。其次，我们最近启动了风湿病学的一项新的重大临床试验计划，主要集中在风湿病的新生物疗法的研究上。这一新计划及其教职员工将极大地扩大对临床研究有主要兴趣的博士后研究员的培训机会。加州大学旧金山分校的风湿病学和临床免疫学课程为医学系教职员工和免疫学研究生课程的教职员工之间的互动和合作提供了一个出色的环境。此外，基础研究中的科学家和临床研究中的科学家之间的实质性互动，以及成人和儿科风湿病学员的综合研究经验，创造了一种尊重我们学科所有方面的氛围。该计划旨在支持六名高素质的个人通过两到三年的严格科学培训，目标是他们将在随后的职业生涯中致力于风湿性和免疫性疾病的研究。

The overall goal of the Academic Rheumatology and Clinical Immunology Training Program at UCSF is to provide advanced training in biomedical research and in health services research to qualified individuals with M.D., M.D./Ph.D., or Ph.D. degrees who plan to pursue careers in academic rheumatology. A major objective of this program is to provide trainees with an environment in which they can: (1) undertake formal didactic course work in a chosen area of concentration; (2) learn how to investigate a scientific problem in depth; master state-of-the-art research techniques; and (4) understand what constitutes good science. In the past, training in our program has taken advantage of the resources of the Rheumatology Divisions of the Department of Medicine at UCSF: one at Moffitt-Long University Hospital, one at San Francisco General Hospital, and one at the San Francisco A Medical Center. These divisions have particular strength in two of the most rapidly developing areas of medical science-biomedical research in immunology and molecular biology, and health service research with an emphasis on outcomes research. These areas of strength are responsive to the unprecedented recent advances in basic science and to the important national changes in health care delivery. In this competitive renewal application, we propose to further strengthen our program in two crucial areas. First, we propose to include research training for postdoctoral fellows in Pediatric Rheumatology. In recent years, UCSF has build one of the top clinical programs in Pediatric Rheumatology in the country, and it will be beneficial to trainees in both adult and pediatric rheumatology. to formally integrate the research programs. Second, we recently initiatived a major new clinical trials program in Rheumatology, focused primarily on the study of novel biologic therapies for rheumatic diseases. This new program, and its faculty, will substantially expand training opportunities for postdoctoral fellows who have a primary interest in clinical research. The Rheumatology and Clinical Immunology program at UCSF provides an outstanding environment of interaction and collaboration among faculty in the Department of Medicine and faculty in the graduate program in Immunology. Furthermore, substantive interactions between scientists in basic research and scientists in clinical research, as well as integrated research experiences for trainees in adult and pediatric rheumatology, create an atmosphere of respect for all aspects of our discipline. The program is intended to support six highly qualified individuals through two or three years of rigorous scientific training, with the objective that they will devote their subsequent careers to the study of the rheumatic and immunologic diseases.