Discovering novel molecules that regulate axonal degeneration.

发现调节轴突变性的新分子。

• 批准号: nhmrc : GNT1108489
• 负责人: Dr Sean Coakley
• 金额: $ 58.86万
• 依托单位国家: 澳大利亚
• 项目类别: Boosting Dementia Research Initiative
• 财政年份: 2016
• 资助国家: 澳大利亚
• 起止时间: 2016-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/discovering-novel-molecules-axonal-degeneration/1346647
• 关键词: Discovering; novel; molecules; regulate; axonal

The axon is the primary signaling component of every neuron and is essential for normal function. Axonal degeneration is a key early pathological hallmark of Alzheimer’s disease. We lack a basic understanding of molecules that regulate this process. Such knowledge is essential for the development of treatments and therapies for dementia and the preservation of healthy ageing. I aim to discover the molecules that regulate axonal degeneration and study their function.

轴突是每个神经元的主要信号成分，对正常功能至关重要。轴突变性是阿尔茨海默病的一个关键的早期病理标志。我们对调节这一过程的分子缺乏基本的了解。这些知识对于发展痴呆症的治疗和疗法以及保持健康的老龄化至关重要。我的目标是发现调节轴突变性的分子并研究它们的功能。