CHILDRENS CANCER GROUP--COMPETITIVE GRANT RENEWAL

儿童癌症组——竞争性拨款更新

• 批准号: 6124650
• 负责人: DAVID L BAKER
• 金额: $ 6.84万
• 依托单位: PRINCESS MARGARET HOSPITAL FOR CHILDREN
• 依托单位国家: 美国
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-01-20 至 2003-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6124650
• 关键词: acute lymphocytic leukemia; acute myelogenous leukemia; antineoplastics; bone marrow transplantation; bone neoplasms; brain neoplasms; clinical research; clinical trials; combination cancer therapy; combination chemotherapy; cooperative study; cytogenetics; data management; human subject; human therapy evaluation; liver neoplasms; lymphoma; molecular oncology; neoplasm /cancer chemotherapy; neoplasm /cancer diagnosis; neoplasm /cancer epidemiology; neoplasm /cancer immunotherapy; neoplasm /cancer pharmacology; neoplasm /cancer radiation therapy; neoplasm /cancer surgery; neuroblastoma; oncology nursing; pediatric neoplasm /cancer; statistics /biometry; tissue resource /registry

Princess Margaret Hospital for Children (PMH) is the sole tertiary university affiliated paediatric teaching hospital for the State of Western Australia and provides the only multidisciplinary paediatric oncology service in the state, which has a population of 2 million. PMH is the only hospital outside North America honoured by being accepted as a CCG member (elected November 1990). Promotion from probationary to full membership was achieved in November 1992. In the last 12 months PMH has entered 70 patients on CCG therapeutic, biologic and non- therapeutic studies. With respect to the overall institutional ranking for 1997 based on a standardised CCG ranking system, PMH achieved a ranking of 19 (compared with 26 in 1996), the best incremental improvement of all CCG affiliated hospitals. The Oncology Division is housed in a purpose built "Total Care Unit" containing all services and disciplines in the one locality needed to manage children with cancer their families and includes inpatient, haemopoietic stem cell transplant, same day care, outpatient, treatment rooms, pharmacy, data management, social work, school room and nurse liaison facilities. The Oncology Division goals are four-fold: (1) Provide state of the art multidisciplinary management which will maximise probabilities of cure for oncological diseases in children. (2) Tailor curative therapy to minimise both acute toxicity and long term deleterious sequelae. (3) Support scientifically sound clinical research through the application of IRB approved co- operative group clinical trials. (4) Promote translational research through active support of CCG approved biologic studies. These aims are best achieved by PMH's commitment to fulfilling all the requirements and responsibilities necessary in maintaining full membership with the Children's Cancer Group. The long term objective of the Oncology Division at PMH is to play a more pro-active role in CCG activities including steering and study committees and strategy group membership.

玛格丽特公主儿童医院 (PMH) 是西澳大利亚州唯一一所三级大学附属儿科教学医院，提供该州唯一的多学科儿科肿瘤服务，该州拥有 200 万人口。 PMH 是北美以外唯一一家荣幸地被接受为 CCG 成员的医院（1990 年 11 月当选）。 1992 年 11 月，从试用会员晋升为正式会员。在过去 12 个月中，PMH 已让 70 名患者接受 CCG 治疗、生物学和非治疗研究。 就1997年基于标准化CCG排名系统的整体机构排名而言，PMH取得了第19名（1996年为26名），是所有CCG附属医院中进步最好的。 肿瘤科设在一个专门建造的“全面护理单元”内，其中包含在一个地方管理癌症儿童及其家人所需的所有服务和学科，包括住院、造血干细胞移植、当天护理、门诊、治疗室、药房、数据管理、社会工作、教室和护士联络设施。肿瘤科的目标有四个：(1) 提供最先进的多学科管理，最大限度地提高儿童肿瘤疾病的治愈率。 (2) 制定治疗方案以尽量减少急性毒性和长期有害后遗症。 (3) 通过应用IRB批准的合作小组临床试验来支持科学合理的临床研究。 (4) 通过积极支持CCG批准的生物学研究来促进转化研究。这些目标最好通过 PMH 承诺履行维持儿童癌症小组正式会员资格所需的所有要求和责任来实现。 PMH 肿瘤科的长期目标是在 CCG 活动中发挥更积极的作用，包括指导和研究委员会以及战略小组成员资格。