PERFUSION IMAGING OF BRAIN, KIDNEY, & HEART

该中心有使用其资源进行试点的规定 并进行可行性试验，而不需要 要求由科学咨询委员会审查。这些 实验通常持续时间较短，并为 目的是获得非常有限的一组数据。这些资源是 由署长酌情分配。核磁共振中心有 在这方面协助了几个小组：(1)获得高分辨率的MR 大鼠大脑的图像，用于制作大鼠脑部的图谱 用于PET数据的大鼠大脑，(Ii)获得高分辨率磁共振图像 建立人体心脏标本的生物力学模型 心脏，(Iii)获得固定人脑的高分辨率磁共振图像， (Iv)获取有关大鼠模型脑血流灌注图的额外数据 蛛网膜下腔出血来完成一项研究 和(V)获得表观扩散系数(ADC) 溶栓性卒中大鼠的脑血流图和脑血流图 模特。核磁共振中心有限时间的分配 及时提供扫描仪的目的是非常有用的 调查人员有时需要的数据最少 延迟。在过去，一些调查人员曾利用这一点 处长在取得领港员资料以供申请时的酌情时间 用于赠款支持，用于进行可行性研究，这些研究是 用于设计新的实验，这些实验随后被进行 在核磁共振中心作为常规项目，并用于捆绑未完成的 此前曾在该中心进行过实验。

The Center has provision for the use of its resources for pilot and feasibility experiments to be carried out without the need for the request to be reviewed by the Scientific Advisory Committee. These experiments are usually of short duration and carried out for the purpose of obtaining a very limited set of data. These resources are allocated at the discretion of the Director. The NMR Center has assisted several groups in this regard: (i) obtain high resolution MR images of the rat brain for the purpose of preparing an atlas of the rat brain for use with PET data, (ii) obtain high-resolution MR images of an isolated human heart specimen for modeling biomechanics of the heart, (iii) obtain high-resolution MR images of a fixed human brain, (iv) obtain additional data on cerebral perfusion maps of a rat model with subarachnoid hemorrhage to complete a study that was carried out the previous year, and (v) obtain apparent diffusion coefficient (ADC) maps and perfusion maps of the rat brain in a photothrobolytic stroke model. Allocation of a limited amount of NMR Center's time on the scanners in a timely manner serves a very useful purpose of providing the investigators data which are sometimes required with minimal delay. In the past, a number of investigators have used this Director's discretionary time for obtaining pilot data for applying for grant support, for carrying out feasibility studies which were used in designing new experiments that were subsequently carried out in the NMR Center as regular projects, and for tying up loose ends of previosly carried out experiments in the Center.