课题基金 / 基金详情

BONE DENSITY IN SURVIVORS OF PEDIATRIC ACUTE LYMPHOBLASTIC LEUKEMIA

BONE DENSITY IN SURVIVORS OF PEDIATRIC ACUTE LYMPHOBLASTIC LEUKEMIA
小儿急性淋巴细胞白血病幸存者的骨密度
批准号：
6264297
负责人：
NINA S KADAN-LOTTICK
金额：
$1.99万
依托单位：
UNIVERSITY OF COLORADO DENVER
依托单位国家：
美国
项目类别：
财政年份：
1998
资助国家：
美国
项目状态：
已结题
起止时间：
1998-12-01 至 1999-11-30
来源：
https://reporter.nih.gov/project-details/6264297
关键词：
acute lymphocytic leukemia blood disorder chemotherapy bone density bone metabolism disorder child (0-11) clinical research comorbidity disease /disorder proneness /risk human subject human therapy evaluation long term survivor neoplasm /cancer chemotherapy neoplasm /cancer epidemiology osteopenia osteoporosis pediatric neoplasm /cancer

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中文摘要
翻译
白血病过程和化疗药物对急性淋巴细胞白血病（ALL）患儿骨代谢的破坏可能降低骨量峰值，使这些个体易患骨质疏松症和骨质减少症。这项横断面研究将确定ALL幸存者中骨质减少和骨质疏松的患病率，并确定相关的危险因素。
英文摘要
Disruption of bone metabolism in children with acute lymphoblastic leukemia (ALL) by both leukemic processes and chemotherapeutic drugs potentially decreases peak bone mass, predisposing these individuals to osteoporosis and osteopenia. This cross-sectional study will determine the prevalence of osteopenia and osteoporosis in survivors of ALL and identify associated risk factors.
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