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MOLEC MODEL OF COFILIN REGULATION IN ACTIN FILAMENT DYNAMICS & CELL FUNCTIONS

MOLEC MODEL OF COFILIN REGULATION IN ACTIN FILAMENT DYNAMICS & CELL FUNCTIONS
肌动蛋白丝动力学中 Cofilin 调节的分子模型
批准号：
6120882
负责人：
AMY M MCGOUGH
金额：
$2.26万
依托单位：
BAYLOR COLLEGE OF MEDICINE
依托单位国家：
美国
项目类别：
财政年份：
1998
资助国家：
美国
项目状态：
已结题
起止时间：
1998-12-01 至 1999-11-30
来源：
https://reporter.nih.gov/project-details/6120882
关键词：
biomedical resource enzymes eye human tissue orphan disease /drug

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英文摘要
Vision in vertebrate retinas is initiated by a light-activated G protein coupled pathway located on disc membranes in the photoreceptor cells. Signaling through this pathway involves the formation and activation of a variety of membrane-dependent protein complexes. We are studying the structures of these complexes as they exist on membrane surfaces through electron crystallography. We have formed two-dimensional crystals and helical arrays of the heterotrimeric form of the G protein and imaged them by cryo-electron microscopy. Image processing of the helical structures has revealed layer lines in the computed Fourier transform to beyond 18 , and indexing of these transforms is in progress.
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MOLECULAR MODEL OF AN ACTIN FILAMENT CAPPED BY SEVERING PROTEIN, GELSOLIN
  • 批准号：
    6568609
  • 项目类别：
  • 资助金额：
    $13.47万
  • 财政年份：
    2001
  • 负责人：
    AMY M MCGOUGH
  • 依托单位：
    BAYLOR COLLEGE OF MEDICINE
MOLECULAR MODEL OF COFILIN REG IN ACTIN FILAMENT DYNAMICS & CELL FUNCTIONS
  • 批准号：
    6611277
  • 项目类别：
  • 资助金额：
    $13.47万
  • 财政年份：
    2001
  • 负责人：
    AMY M MCGOUGH
  • 依托单位：
    BAYLOR COLLEGE OF MEDICINE
MOLECULAR MODEL OF COFILIN REG IN ACTIN FILAMENT DYNAMICS & CELL FUNCTIONS
  • 批准号：
    6568608
  • 项目类别：
  • 资助金额：
    $13.47万
  • 财政年份：
    2001
  • 负责人：
    AMY M MCGOUGH
  • 依托单位：
    BAYLOR COLLEGE OF MEDICINE
MOLECULAR MODEL OF AN ACTIN FILAMENT CAPPED BY SEVERING PROTEIN, GELSOLIN
  • 批准号：
    6611278
  • 项目类别：
  • 资助金额：
    $13.47万
  • 财政年份：
    2001
  • 负责人：
    AMY M MCGOUGH
  • 依托单位：
    BAYLOR COLLEGE OF MEDICINE
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