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POSTMENOPAUSAL BMD

POSTMENOPAUSAL BMD
绝经后骨密度
批准号：
6265509
负责人：
NORMAN L BELL
金额：
$1.74万
依托单位：
MEDICAL UNIVERSITY OF SOUTH CAROLINA
依托单位国家：
美国
项目类别：
财政年份：
1998
资助国家：
美国
项目状态：
已结题
起止时间：
1998-12-01 至 1999-11-30
来源：
https://reporter.nih.gov/project-details/6265509
关键词：
alendronate bone density clinical research dosage drug adverse effect drug screening /evaluation female human subject human therapy evaluation longitudinal human study postmenopause skeletal disorder chemotherapy

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中文摘要
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英文摘要
To compare the effects on lumbar spine BMD of 1 year of treatment with alendronate 35 mg once weekly compared to treatment with 5 mg daily in postmenopausal women. To assess the safety and tolerablility of 1 year of treatment with alendronate 35 mg once weekly compared to treatment with 5 mg daily in postmenopausal women. To compare the effects of BMD of the hip and total body of 1 year treatment with alendronate 35 mg once weekly with those of 5 mg daily in postmenopausal women. To assess the effect of 1 and 2 years of treatment with alendronate 35 mg once weekly compared to treatment with alendronate 5 mg daily on the rate of bone turnover as assessed by biochemical markers (NTx and BSAP) in postmenopausal women. To assess the effect of 2 years of treatment with alendronate 35 mg once weekly compared to treatment with alendronate 5 mg daily in postmenopausal women on (a) BMD at the lumbar spine, hip, and total body, and (b) safety and tolerability.
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POSTMENOPAUSAL OSTEOPOROSIS
POSTMENOPAUSAL OSTEOPOROSIS
POSTMENOPAUSAL OSTEOPOROSIS
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