PREGABALIN INPATIENT MONOTHERAPY TRIAL IN REFRACTORY PARTIAL EPILEPSY

普瑞巴林住院难治性部分性癫痫单一疗法试验

• 批准号: 6265739
• 负责人: RAJ D SHETH
• 金额: $ 3.35万
• 依托单位: UNIVERSITY OF WISCONSIN-MADISON
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-12-01 至 1999-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6265739
• 关键词: anticonvulsants; brain disorder chemotherapy; clinical research; drug adverse effect; drug screening /evaluation; epilepsy; human subject; human therapy evaluation

This study proposes to evaluate the efficacy and safety of pregabalin at 600 mg/day as compared with gabapentin 300 mg/day in patients with complex partial seizures, with or without secondary generalization, who have had their concomitant antiepileptic drugs (AEDs) discontinued as part of an inpatient hospitalization for clinical seizure monitoring.

本研究旨在评价普瑞巴林600 mg/d与加巴喷丁300 mg/d相比在复杂部分性癫痫发作（伴或不伴继发全身性发作）患者中的疗效和安全性，这些患者在住院期间停用了伴随使用的抗癫痫药物（AED），以进行临床癫痫发作监测。