CORE-- MOLECULAR BIOLOGY

核心--分子生物学

• 批准号: 6107534
• 负责人: THOMAS A PRESSLEY
• 金额: --
• 依托单位: UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-07-01 至 1999-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6107534
• 关键词: biomedical facility; genetic library; molecular biology; monoclonal antibody; northern blottings; nucleic acid probes; plasmids; western blottings

Several projects within the Trauma Center will include efforts to examine the expression of specific proteins. Because of low abundance or the absence of enzymatic activity (e.g., the cytokines) the evaluation of many of these proteins will require specific nucleic acid and antibody probes. The Molecular Biology core will allow us to centralize expertise and instruments in a facility designed to assist investigators in the development and use of such probes. Through active participation in research seminars and workshops, the Core will also play an important training role for investigators and their colleagues.

创伤中心内的几个项目将包括努力检查 特定蛋白质的表达。 由于低丰度或 缺乏酶活性（例如，细胞因子）的评价 这些蛋白质中的许多将需要特定的核酸和抗体 probes. 分子生物学核心将使我们能够集中专业知识 和仪器的设施，旨在协助调查人员在 开发和使用这种探针。 通过积极参与 研究研讨会和讲习班，核心也将发挥重要作用， 对研究者及其同事的培训作用。