ALDOSE REDUCTASE GENE EXPRESSION IN DIABETIC COMPLICATIONS
ALDOSE REDUCTASE GENE EXPRESSION IN DIABETIC COMPLICATIONS
批准号:
6244587
负责人:
DOUGLAS N HENRY
金额:
$2.22万
依托单位国家:
美国
项目类别:
财政年份:
1997
资助国家:
美国
项目状态:
已结题
起止时间:
1997-02-20 至 1997-11-30
中文摘要
点击翻译按钮获取中文摘要
英文摘要
The overall aim of this application is to characterize the mechanism(s)
regulating aldose reductase (AR2,EC1.1.1.21) gene expression in cells
from tissues involved in the complications of diabetes, and to determine
the basis for abnormal constitutive over-expression of AR2 by a line of
human retinal pigment epithelial (RPE) cells. The rationale for this
proposal rests on the postulated role of AR2 in the genesis of the
chronic complications of diabetes, and the growing evidence that AR2
particpates in, and is modulated by, physiological osmoregulation.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
ALDOSE REDUCTASE EXPRESSION IN DIABETES
-
批准号:2391249
-
项目类别:
-
资助金额:$8.92万
-
财政年份:1993
-
负责人:DOUGLAS N HENRY
-
依托单位:
ALDOSE REDUCTASE EXPRESSION IN DIABETES
-
批准号:2133987
-
项目类别:
-
资助金额:$7.88万
-
财政年份:1993
-
负责人:DOUGLAS N HENRY
-
依托单位:
ALDOSE REDUCTASE EXPRESSION IN DIABETES
-
批准号:3086627
-
项目类别:
-
资助金额:$7.88万
-
财政年份:1993
-
负责人:DOUGLAS N HENRY
-
依托单位:
ALDOSE REDUCTASE EXPRESSION IN DIABETES
-
批准号:2133989
-
项目类别:
-
资助金额:$8.92万
-
财政年份:1993
-
负责人:DOUGLAS N HENRY
-
依托单位:
ALDOSE REDUCTASE EXPRESSION IN DIABETES
-
批准号:2133988
-
项目类别:
-
资助金额:$7.71万
-
财政年份:1993
-
负责人:DOUGLAS N HENRY
-
依托单位:
ALDOSE REDUCTASE GENE EXPRESSION IN DIABETIC COMPLICATIONS
-
批准号:5217611
-
项目类别:
-
资助金额:$0.0万
-
财政年份:--
-
负责人:DOUGLAS N HENRY
-
依托单位:--
海外基金