HIV 链球菌的咽部携带率和耐药模式-猫眼课题宝

HIV 链球菌的咽部携带率和耐药模式

批准号：

6245334

负责人：

RODNEY WILLOUGHBY

金额：

$2.23万

依托单位：

JOHNS HOPKINS UNIVERSITY

依托单位国家：

美国

项目类别：

财政年份：

1997

资助国家：

美国

项目状态：

已结题

起止时间：

1997-03-05 至 1997-11-30

来源：

https://reporter.nih.gov/project-details/6245334

关键词：

HIV infections Pneumocystis pneumonia Streptococcus pneumoniae blood toxicology case history chemoprevention child (0-11) clinical research drug resistance human subject pediatric AIDS pharyngitis sulfamethoxazole trimethoprim

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英文摘要

This case control study of the prevalence of colonization of the pneumococcus in HIV-infected children was begun on December, 1996 and is currently ongoing. This study will be significant in that it will define for the first time possible mechanisms behind the protective effect against blood infection with pneumococci of cotrimoxazole prophylaxis against an unrelated disease, PCP. It will also define whether cotrimoxazole prophylaxis influences the resistance pattern of penumococci, currently a major emerging pathogen as defined by the Centers for Disease Control. In addition, this study inaugurates the concept of "PCRU-on-wheels". The study is being conducted by PCRU staff in 4 clinic locations, with central processing and data collection in the PCRU.

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