BENZO(A)PYRENE DNA ADDUCT FORMATION IN HUMAN PREGNANCY

人类妊娠期间苯并(A)芘 DNA 加合物的形成

• 批准号: 6246039
• 负责人: DAVID K MANCHESTER
• 金额: $ 1.71万
• 依托单位: UNIVERSITY OF COLORADO DENVER
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-03-20 至 1997-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6246039
• 关键词: DNA; adduct; benzopyrenes; carbopolycyclic compound; gene mutation; human genetic material tag; human tissue; placenta; pregnancy; teratogens

In this project we will measure Benzo (a) pyrene-DNA adducts in human placenta. The focus of this research is on identification of other PAH- DNA adducts in placental DNA and on development of a system to investigate the mechanisms by which PAH-DNA adducts cause mutation in human cells.

在本项目中，我们将测量人体内苯并（a）芘-DNA加合物 胎盘 本研究的重点是识别其他PAH- 胎盘DNA中的DNA加合物和研究系统的开发 PAH-DNA加合物导致人类细胞突变的机制。