EPIDEMIOLOGY OF HUMAN RETROVIRUSES IN BLOOD DONORS

献血者中人类逆转录病毒的流行病学

• 批准号: 6358868
• 负责人: GEORGE GARRATTY
• 金额: --
• 依托单位: AMERICAN NATIONAL RED CROSS LOS ANGELES
• 依托单位国家: 美国
• 财政年份: 1989
• 资助国家: 美国
• 起止时间: 1989-07-17 至 2003-09-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6358868
• 关键词: HIV infections; Retroviridae; antiviral antibody; blood banks; blood donor; clinical research; communicable disease control; disease /disorder proneness /risk; epidemiology; hepatitis B; hepatitis C; human T cell lymphotropic virus type 1; human T cell lymphotropic virus type 2; human immunodeficiency virus 1; human immunodeficiency virus 2; human subject; longitudinal human study; mass screening; serology /serodiagnosis

The objective of this contract are as follows: 1) determine the prevalence of retrovirus seropositivity in first time blood donors; 2) determine the rate of retrovirus seroconversion in repeat blood donors as a measure of incidence of infection; 3) ascertain risk factors for antibody-positive donors; 4) characterize the blood donor population by geographic location, age, sex, race/ethnicity, and donation history to permit analysis on prevalence, incidence, and risk factors; 5) identify recipients of retrovirus-positive blood units and conduct clinical and laboratory follow-up of these recipients to determine the transmissibility of these agents via transfusion; and 6) establish blood specimen repositories for long-term storage of specimens from study donors and recipients for future testing.

本合同的目的如下：1)确定

项目成果

Evaluation of a p21e-spiked western blot (immunoblot) in confirming human T-cell lymphotropic virus type I or II infection in volunteer blood donors. The Retrovirus Epidemiology Donor Study Group.

评估 p21e 蛋白印迹（免疫印迹）在确认志愿者献血者中人类 T 细胞嗜淋巴细胞病毒 I 型或 II 型感染方面的作用。

• DOI: 10.1128/jcm.32.3.603-607.1994
• 发表时间: 1994
• 期刊: Journal of clinical microbiology
• 影响因子: 9.4
• 作者: Kleinman,SH;Kaplan,JE;Khabbaz,RF;Calabro,MA;Thomson,R;Busch,M
• 通讯作者: Busch,M