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(SAME SD4) ON METHIONINE METABOLIC IMPAIRMENT AND CHOLESTASIS IN CIRRHOSIS

(SAME SD4) ON METHIONINE METABOLIC IMPAIRMENT AND CHOLESTASIS IN CIRRHOSIS
（相同 SD4）关于肝硬化中的蛋氨酸代谢损伤和胆汁淤积
批准号：
6113830
负责人：
IAN S GRIMM
金额：
$1.58万
依托单位：
UNIV OF NORTH CAROLINA CHAPEL HILL
依托单位国家：
美国
项目类别：
财政年份：
1998
资助国家：
美国
项目状态：
已结题
起止时间：
1998-12-01 至 1999-11-30
来源：
https://reporter.nih.gov/project-details/6113830
关键词：
biliary tract disorder chemotherapy bilirubin cholestasis clinical research clinical trial phase I human subject human therapy evaluation liver cirrhosis liver disorder chemotherapy metabolism disorder metabolism disorder chemotherapy methionine

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中文摘要
翻译
本研究的目的是评价一种抗肿瘤药物的安全性和有效性
英文摘要
The purpose of this study is to evaluate the safety and efficacy of an investigational drug called SAMe SD4 in patients with cirrhosis. It is proposed that patients with liver cirrhosis have defects in metabolism which lead to the buildup of waste products in the blood. This new compound is designed to replace one link in the chain which may restore proper metabolism to patients. Outcome parameters will be serum total bilirubin and response to methionine overload.
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