CORE--CLINICAL TRIALS RESEARCH OFFICE

临床试验研究办公室(CTRO)提供基础设施和 促进必要的协调以支持高质量的临床 在一个母体式癌症中心进行研究。这项科学由 CTRO涵盖从Pilot开始的所有级别和类型的临床试验 研究和第一阶段协议至第二阶段和第三阶段协议。这些 协议可以是由UWCCC调查员发起的机构或行业 赞助的临床试验，或者它们可能是NCI赞助的临床试验 通过合作小组、第一阶段或研究基金提供资金 机械装置。CTRO临床研究基础设施由 CCSG补助金旨在通过以下方式促进和促进临床研究 提供有效的质量控制和效率机制。 CTRO的UWCCC核心组件提供了基本级别的协议- 为所有UWCCC临床试验提供具体支持。这包括流程 协调；议定书激活和关闭；通过UWCCC数据进行跟踪 基础；监管审查和合规性；患者登记和 随机化；和质量保证。CTRO支持该协议 评审和监控系统，为质量控制提供检查点 以及为执行机构权威而开放和关闭 协议。它确保关于协议活动的完整报告和有意义的 癌症中心对癌症临床研究的监督 机构。

The Clinical Trials Research Office (CTRO) provides the infrastructure and facilitates the coordination necessary to support high quality clinical research in a matrix style cancer center. The science supported by the CTRO encompasses all levels and types of clinical trials, from pilot studies and phase I protocols through phase II and III protocols. These protocols may be UWCCC investigator-initiated institutional or industry sponsored clinical trials, or they may be NCI-sponsored clinical trials funded through the cooperative group, phase I, or research grant mechanisms. The CTRO infrastructure for clinical research supported by the CCSG grant is designed to facilitate and promote clinical research by providing effective mechanisms for quality control and efficiency. The UWCCC core component of the CTRO provides a basic level of protocol- specific support for all UWCCC clinical trials. This includes process coordination; protocol activation and closure; tracking by the UWCCC data base; regulatory review and compliance; patient registration and randomization; and quality assurance. The CTRO supports the Protocol Review and Monitoring System, providing checkpoints for quality control and for enforcement of the institutional authority to open and close protocols. It ensures complete reports on protocol activity and meaningful cancer center supervision of the cancer clinical research in the institution.