SIGNAL PROCESSING FOR ENHANCED TISSUE IMAGING

该项目的主要目标是根据组织的 来自受辐射组织区域的超声回声。世界各地的 组织将被分为正常和异常基于一组 将在拟议的基础上制定的标准 调查。拟议的研究是基于这样一个前提，即 来自肝脏和乳房组织的超声回波可以使用 K分布。K分布的参数似乎是成立的 有关组织性质的信息，正常或异常，或良性或 恶性的。此外，回声的非瑞利性质可能是 扩展到包括相位统计量的影响及其 与病变组织和正常组织的关系。这些非瑞利方面 后向散射回波的包络和相位信息 组织的B超图像，将被广泛用于实现 组织定征的主要目标。 我们将使用标准的ROC来研究我们技术的有效性 分析。基于大量的患者和多次扫描 在患者中，将有足够的数据集可用来进行 对本研究中开发的方法进行最终评估。 这项研究将使用由 来自托马斯·杰斐逊大学的临床核心小组。这些技术 通过这项研究开发的将因此被用来提出 筛查癌症(乳腺癌和肝癌)患者的策略 检查B超扫描结果。希望这次会议的结果 研究将会开发出一种低成本、更简单的方法 用于使用超声波筛查癌症患者，一种非电离的 辐射。

The primary goal of the project is to characterize the tissue based on the ultrasonic echo from the insonated tissue regions. The regions of the tissue will be classified as normal and abnormal based on a set of criteria that will be developed on the basis of the proposed investigations. The proposed research is based on the premise that the ultrasound echo from liver as well as breast tissue may be modeled using the K-distribution. The parameter of the K-distribution appears to hold information on the nature of the tissue, normal or abnormal, or benign or malignant. Further more, the non-Rayleigh nature of the echo could be extended to include the effect of the phase statistics and its relationship to the diseased and normal tissue. These non-Rayleigh aspects of the back-scattered echo, in terms of the envelope and phase information of the B scan image of the tissue, will be extensively used to achieve the major goal of tissue characterization. The efficacy of our techniques will be studied using the standard ROC analyses. Based on the large number of patients as well as multiple scans of the patients, there will be sufficient data sets available to make a definitive evaluation of the methodologies developed in this research. The research will be undertaken using the patient data supplied by the clinical core group from Thomas Jefferson University. The techniques developed through this research will therefore be used to propose strategies for the screening of patients for cancer (breast and liver) by examining the ultrasound B-scans. It is hoped that outcomes of this research will be such that a low cost simpler method could be developed for the screening of patients for cancer using ultrasound, a non-ionizing radiation.