Dissecting the molecular mechanisms underlying muscle pathology in Duchenne Muscular Dystrophy (DMD)

剖析杜氏肌营养不良症 (DMD) 肌肉病理学的分子机制

• 批准号: nhmrc : 575580
• 负责人: Dr Kristy Swiderski
• 金额: $ 25.06万
• 依托单位: The University of Melbourne
• 依托单位国家: 澳大利亚
• 项目类别: Early Career Fellowships
• 财政年份: 2009
• 资助国家: 澳大利亚
• 起止时间: 2009-01-01 至 2014-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/dissecting-molecular-mechanisms-dystrophy-dmd/116232
• 关键词: Dissecting; molecular; mechanisms; underlying; muscle

Duchenne Muscular Dystrophy (DMD) is a genetic disease affecting 1-3,500 newborn males worldwide annually. The disease is characterized by muscle wasting, subsequently resulting in fatality in the late teens to the late 20's. To date there is no cure and treatments are aimed improving quality of life. This project focuses on examining the mechanisms behind the disease to ultimately gain a better understanding in order to develop more effective therapies for the treatment of DMD.

杜氏肌营养不良症（DMD）是一种遗传性疾病，每年影响全球1- 3，500名新生男性。这种疾病的特征是肌肉萎缩，随后导致在青少年后期至20年代后期的死亡。迄今为止，还没有治愈的方法，治疗的目的是提高生活质量。该项目的重点是研究疾病背后的机制，最终获得更好的理解，以开发更有效的治疗DMD的疗法。