IMMUNOSCANNING ELECTRON MICROSCOPY OF HERPES VIRUSES

疱疹病毒的表面还没有经过严格的分析。 近年来，尽管重组DNA技术已经允许 人工合成衣壳的重建。这个实验室的利益 是针对病毒的结构：功能关系 疱疹病毒包膜中发现的糖蛋白 凯西德。在最近一项使用高分辨率免疫扫描的研究中 电子显微镜(J.E.M.46：171,1997：) 糖蛋白在细胞表面定位的不同模式 病毒粒子。上述研究也未能证明典型的“尖峰”现象 传统上在较老的出版物中描述的“表格”。 未来的研究将在更高的水平上检查病毒表面的投影 决议。

The surface of the herpesvirion has not been rigorously analyzed in recent years, even though recombinant DNA technology has allowed reconstruction of synthetic capsids. The interest of this laboratory is directed towards the structure: function relationships of viral glycoproteins found in the envelope which surrounds the herpesviral capsid. In a recent study using high resolution immunoscanning electron microscopy (J.E.M. 46: 171, 1997:, we demonstrated markedly different patterns of glycoprotein localization on the surface of the virion. The above study also failed to demonstrate the typical "spike forms" which have been traditionally described in older publications. Future studies will examine the viral surface projections at a higher resolution.