课题基金 / 基金详情

STUDY OF TEMOZOLOMIDE IN TREATMENT OF GLIOBLASTOMA MULTIFORME AT FIRST RELAPSE

STUDY OF TEMOZOLOMIDE IN TREATMENT OF GLIOBLASTOMA MULTIFORME AT FIRST RELAPSE
替莫唑胺治疗初次复发多形性胶质母细胞瘤的研究
批准号：
6274742
负责人：
HARRY S GREENBERG
金额：
$2.15万
依托单位：
UNIVERSITY OF MICHIGAN AT ANN ARBOR
依托单位国家：
美国
项目类别：
财政年份：
1997
资助国家：
美国
项目状态：
已结题
起止时间：
1997-12-01 至 1998-11-30
来源：
https://reporter.nih.gov/project-details/6274742
关键词：
clinical research drug adverse effect drug screening /evaluation glioblastoma multiforme human subject human therapy evaluation neoplasm /cancer chemotherapy neoplasm /cancer relapse /recurrence quality of life temozolomide

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中文摘要
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英文摘要
A randomized open label phase II study of Temozolomide and reference agent Procarbazine in the treatment of patients with glioblastoma multiforme at first relapse after surgery, external beam chemotherapy and at most one chemotherapy regimen. Efficacy will defined as six month progression free survival. Secondary measures will be quality of life and survival. Toxicity will be carefully monitored.
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