COCAINE EXPOSED INFANTS--CARDIAC PROBLEMS AND OUTCOME

怀孕期间使用可卡因的母亲所生的婴儿 发病率和猝死率较高。 突发性心脏病的病因 死亡是不明确的。初步观察表明， 多种心血管异常，如左心室增大 肿块，持续性高血压，ST段的患病率更高 升高和更高的迷走神经张力。 研究对心血管的影响 研究的目的如下： 检测新生儿期的心血管异常; 探讨脐血血浆胆碱酯酶活性与新生儿出生体重的关系 以及上述异常;并研究这些异常的自然历史 异常 在生命的前两个月。

Infants born to mother who use cocaine during pregnancy have greater morbidity and a higher rate of sudden death. The etiology of sudden death is unclear. Preliminary observations suggest the presence of multiple cardiovascular abnormalities such as greater left ventricular mass, persistent hypertension, greater prevalence of ST segment elevations and higher vagal tone. To study the cardiovascular effects on in-utero cocaine exposure the study has the following aims: to detect the cardiovascular abnormalities in the newborn period; to evaluate the relationship of cord blood plasma cholinesterase activity and the above abnormalities; and to study the natural history of these abnormalities during the first 2 months of life.