ACTG 242--PHASE II/III DOUBLE BLIND STUDY OF AMITRIPTYLINE AND MEXILETINE

ACTG 242--阿米替林和美西律的 II/III 期双盲研究

• 批准号: 2785024
• 金额: $ 5.12万
• 依托单位: MOUNT SINAI SCHOOL OF MEDICINE OF CUNY
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/2785024
• 关键词: AIDS therapy; HIV infections; amitriptyline; analgesics; clinical research; combination chemotherapy; drug adverse effect; drug screening /evaluation; human subject; human therapy evaluation; mexiletine; nervous system disorder chemotherapy; pain; pain threshold

The primary objective of this study is to assess the effectiveness of amitriptyline and mexiletine in reducing pain intensity in patients with HIV-related painful neuropathy, as measured by the pain intensity description scale developed by Gracely et al. The study will also assess the safety and tolerability of study treatments.

这项研究的主要目标是评估 阿米替林与美西律联合应用减轻慢性前列腺炎患者的疼痛强度 HIV相关的痛性神经病，以疼痛强度衡量 描述量表由Gracely等人开发。这项研究还将评估 研究治疗的安全性和耐受性。