INSULIN RESPONSE TO PROLONGED HYPERGLYCEMIA IN FIRST DEGREE RELATIVES

一级亲属胰岛素对长期高血糖的反应

• 批准号: 6278194
• 负责人: Guenther Boden
• 金额: $ 1.45万
• 依托单位: TEMPLE UNIV OF THE COMMONWEALTH
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-09-15 至 1998-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6278194
• 关键词: clinical research; family genetics; glucose tolerance; hormone regulation /control mechanism; human subject; hyperglycinemia; insulin; noninsulin dependent diabetes mellitus; pancreatic islets

The specific aim of this project is to investigate whether beta cell adaptation to prolonged hyperglycemia is defective in glucose tolerant first degree relatives with non-insulin dependent diabetes mellitus (NIDDM) as compared with normal subject.

该项目的具体目的是研究β细胞是否 葡萄糖耐量正常者对长期高血糖的适应是有缺陷的， 非胰岛素依赖型糖尿病一级亲属 （NIDDM）与正常人相比。