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DOUBLE BLIND, PLACEBO CONTROLLED STUDY OF CTLA4IG IN PATIENTS WITH PSORIASIS

DOUBLE BLIND, PLACEBO CONTROLLED STUDY OF CTLA4IG IN PATIENTS WITH PSORIASIS
CTLA4IG 在银屑病患者中的双盲、安慰剂对照研究
批准号：
6278175
负责人：
JON M HANIFIN
金额：
$2.86万
依托单位：
OREGON HEALTH & SCIENCE UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
1997
资助国家：
美国
项目状态：
已结题
起止时间：
1997-12-01 至 1998-11-30
来源：
https://reporter.nih.gov/project-details/6278175
关键词：
clinical research drug screening /evaluation human subject human therapy evaluation immunoconjugates immunotherapy pharmacokinetics psoriasis

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中文摘要
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英文摘要
This Phase II study is a multi-center, randomized, placebo-controlled trial designed to assess the safety, pharmacokinetics, pharmacodynamics, immunogenicity, and biologic activity of BMS-188667 (CTLA4Ig) in patients with psoriasis vulgaris. Eligable patients will have stable plaque psoriasis of greater than six months duration, and involvement of at least 10% body surface area (BSA), and will have failed at least one standard anti-psoriatic therapy for toxicity and/or inefficacy. Information from this study will be used in the development of dosing schedules in Phase III studies in this patient population.
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International Symposium on Atopic Dermatitis
DOUBLE BLIND, PLACEBO CONTROLLED STUDY OF CTLA4IG IN PATIENTS WITH PSORIASIS
MONOCYTE CONTROL OF IL 4 EXPRESSION IN ATOPIC DERMATITIS
MONOCYTE CONTROL OF IL 4 EXPRESSION IN ATOPIC DERMATITIS