DIAGNOSTIC & CLINICAL PATHOLOGY

比较病理学分部提供解剖学和 为中心各科室提供临床病理服务， 附属科学家、合作科学家和其他科学工作者 来自新英格兰地区的调查人员利用 这个中心。这些服务的申请数量可以是 分类如下 A.进行尸检的次数为365次 B.处理和检查的活组织标本数量339 C.全血细胞计数(CBCs)数3451 D.其他临床病理要求的数量，包括 粪便检查，化学分析，尿液分析， 细胞学检查和液体分析636 E.为外部调查人员收集的标本数量90 进行了完整的尸检和组织病理学检查 在该中心死亡的所有非人类灵长类动物，包括流产和 来自几个繁殖群体的死胎，死亡的动物 自发性疾病，但没有参与研究项目，以及 那些在特定研究中死亡或被牺牲的动物。 通过检查这些组织产生的数据被用来 监察香港的传染病暴发，以提供 为正在进行的研究提供辅助支持，并提供 为我们的临床兽医人员提供诊断支持。最后， 诊断实验室是认识到某些疾病的基础 圈养非人类灵长类动物的自然疾病，可作为 某些人类疾病的模型状态。这些公认的例子 和之前在该中心的特征包括猿猴艾滋病， 结肠炎和结肠癌，以及肾小球肾炎。非常活跃 关于艾滋病发病机制的大型研究正在进行中 目前在比较病理学分部内，结果 根据这些初步的观察和描述。进一步 最近描述的非人类疾病的特征 灵长类动物正在接受调查，包括出血的素质 Callithrix合并吸收不良和骨质疏松，以及 SIV感染猕猴的动脉病变。

The Division of Comparative Pathology provides anatomic and clinical pathology services to the various Divisions of the Center, affiliated scientists, collaborative scientists and other scientific investigators from the New England area who utilize the resources of this Center. The number of requisitions for these services can be categorized as follows a. Number of post-mortem examinations performed 365 b. Number of biopsy specimens processed and examined 339 c. Number of complete blood counts (CBCs) 3451 d. Number of other clinical pathology requisitions including fecal examinations, chemistry analyses, urinalyses, cytological examinations, and fluid analyses 636 e. Number of specimens collected for outside investigators 90 Complete postmortem and histopathologic examinations were performed on all nonhuman primates that died at the Center including abortuses and stillbirths from the several breeding colonies, animals dying of spontaneous disease while not involved in a research project, and those animals that died or were sacrificed while on specific studies. The data generated from examination of those tissues is used to monitor outbreaks of infectious diseases in our colony, to provide ancillary support for ongoing research studies, and to provide diagnostic support to our clinical veterinary staff. Finally, the diagnostic laboratory is fundamental in the recognition of certain natural diseases of captive nonhuman primates that may be explored as models of certain human diseases states. Examples of these recognized and characterized previously at the Center include simian AIDS, colitis and colonic carcinoma, and glomerulonephritis. Very active and large studies on the pathogenesis of AIDS are ongoing at the present time within the Division of Comparative Pathology, resulting from these initial observations and descriptions. Further characterization of more recently described conditions of nonhuman primates are under investigation, including a bleeding diathesis of Callithrix with concurrent malabsorption and osteoporosis, and arteriopathy in SIV-infected Macaca mulatta.