NEW TRITIUM LABELLING REAGENTS & TECHNIQUES: SYNTHESIS REVIEW ARTICLE

一篇评论文章正在为《合成生物学杂志》（Journal of Synthetic Biology）准备。 有机化学（合成）. 本次审查将提出一个调查， 新型高比活度氚标记试剂， 国家氚标记设施开发的技术， 它们在氚标记化学中的应用。 审查将 根据试剂的类型，其发展和 一些应用程序。 重点将放在试剂和 具有极高合成能力的技术， 高比活度氚标记化合物。 的重点 将审查化学标记合成，不包括 氢-氚交换反应和生物化学方法。 电流 本文的规划建议它将包含六个部分， 如下：1. 导言2. 氚化试剂的合成及应用 3. 氚水的合成与应用4. 用氚气进行多相催化氚化5。 结论6. 参考文献《华尔街日报》编辑要求这篇评论文章 请秘书长在1998年10月之前提交， 期刊编辑委员会。

A review article is in preparation for the Journal of Synthetic Organic Chemistry (Synthesis). This review will present a survey of the new high specific activity tritium labelling reagents and techniques developed at the National Tritium Labelling Facility and their applications to tritium labelling chemistry. The review will be organized on the basis of the type of reagent, its development and some applications. Emphasis will be placed on the reagents and techniques that have exceptionally high capability in the synthesis of high specific activity tritium labelled compounds. The focus of this review will be on chemical labelling synthesis and will not include hydrogen-tritium exchange reactions and biochemical methods. Current planning for this article suggests it will contain six sections as follows: 1. Introduction 2. Synthesis and Applications of Tritiated Tritides 3. Synthesis and Applications of Tritiated Water 4. Heterogeneous Catalytic Tritiation with Tritium Gas 5. Conclusion 6. References The Journal editor has requested that this review article be submitted before October 1998 for editing and revision by the Journal editorial board.