ARTHRITIS DIET AND ACTIVITY PROMOTION TRIAL (ADAPT)

关节炎饮食和活动促进试验 (ADAPT)

• 批准号: 6282802
• 负责人: WALTER ETTINGER
• 金额: $ 3.63万
• 依托单位: WAKE FOREST UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-12-01 至 1998-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6282802
• 关键词: clinical research; combination therapy; exercise; human old age (65+); human subject; human therapy evaluation; knee; nutrition related tag; obesity; osteoarthritis; reducing diet; weight loss

Osteoarthritis (OA) is the most prevalent chronic joint condition. The knee is the second most commonly affected joint by OA (after the hand) and has prevalence in older people. Numerous studies also show that obesity is a strong risk factor for the development of knee OA. When symptoms are present, knee OA can be a major cause of physical disability. This study will test the relative effica-cies of exercise, wieght loss and a combined intervention in the management of osteoarthritis of the knee in older obese subjects.

骨关节炎（OA）是最常见的慢性关节疾病。膝 是第二个最常受OA影响的关节（仅次于手）， 老年人的患病率。许多研究还表明，肥胖是一种 膝关节骨性关节炎发展的强风险因素。当症状都 目前，膝关节OA可能是身体残疾的主要原因。 本研究 将测试运动、减肥和综合运动的相对功效。 老年肥胖者膝关节骨关节炎的干预治疗 科目