IGF BINDING PROTEINS IN PERINATAL GROWTH

围产期生长中的 IGF 结合蛋白

• 批准号: 6282836
• 负责人: STEVEN D CHERNAUSEK
• 金额: $ 2.34万
• 依托单位: CINCINNATI CHILDRENS HOSP MED CTR
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-12-01 至 1998-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6282836
• 关键词: blood chemistry; body composition; body physical characteristic; child physical development; clinical research; developmental nutrition; hormone binding protein; human birth weight; human subject; infant human (0-1 year); insulinlike growth factor; longitudinal human study; newborn human (0-6 weeks); nutrition related tag; perinatal; postnatal growth disorder; preschool child (1-5); umbilical cord

This study examines the interactions between the IGFs, the IGF-BPs, nutrition and growth in young children with both normal and aberrant growth. Concentrations of IGFs and IGF-BPs in cord blood from cohorts of AGA and SGA newborns are being correlated with birthweight and other anthropometric indices. A longitudinal study examines these same indices along with IGF and IGF-BP serum concentrations, nutritional intake and body composition among cohorts of AGA and SGA infants from age 2 weeks to age 3 years.

本研究检测了IGFs，IGF-BP， 营养和生长的幼儿与正常和异常 增长 IGFs和IGF-BPs在脐带血中的浓度 阿加和SGA新生儿与出生体重和其他 人体测量指标 一项纵向研究考察了这些相同的指数 沿着IGF和IGF-BP血清浓度、营养摄入和 阿加和SGA婴儿队列中从2周龄至 年龄3岁。