NNFF Intl Consortium--Molecular Biology of NF1 and NF2

NNFF国际联盟--NF1和NF2的分子生物学

• 批准号: 6359781
• 负责人: Luis Fernando Parada
• 金额: $ 6.85万
• 依托单位: CHILDREN'S TUMOR FOUNDATION
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-04-15 至 2002-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6359781
• 关键词: international health /scientific organization; meeting /conference /symposium; molecular biology; neurofibromatosis; neurofibromatosis type 1 protein /gene; travel

DESCRIPTION (provided by applicant): We request funding for the next meeting of the International Consortium for the Molecular Biology of NF 1 and NF2 to be held May 20-23, 2001 at the hotel Jerome in Aspen Colorado. Under the organization of the National Neurofibromatosis Foundation (NNFF), these Consortium meetings have been held on a yearly basis and have served to consolidate the efforts of cell biologists, molecular biologists, and clinicians. Previous meetings led to the identification and cloning of the NF1 and NF2 genes; and facilitated understanding of their structure and function. Since 1995, the yearly meeting has alternated between a larger open format for which announcement is widespread and includes invitation for submission of abstracts by NF researchers throughout the world and a more limited format, in which specific participants and discussants are invited to participate. This latter format provides opportunity for increased discussion and focussing of strategic plans for the future. This year, we propose to bring in specialists from outside the NF field to evaluate current NF research. These will include leading experts in signal transduction, tumorigenesis, cytoplasm organization, and other areas. Each session will be co-chaired by an NF researcher and an outside specialist whose function will be not only to present a research talk but also to assist in guiding the discussion and evaluating the work in NF as it relates to state of the art approaches in each field. Selection of invited speakers has been made with an effort to include all pertinent areas of NF research with emphasis on recent advances. In six sessions, 4 speakers will be allowed 25 minutes for presentation and an additional 20 minutes for discussion. At the end, the "expert co-chair" will be asked to summarize in the context of the larger picture. To ensure the participation of young investigators, each participant will be invited together with one junior member of their laboratory (graduate student or postdoctoral fellow). We expect this opportunity to stimulate the interest of young scientists to pursue NF research (particularly those coming for the expert co-chair laboratories). We anticipate that this format will emphasize new breakthroughs and serve to identify of critical gaps in current approaches and/or understanding. The overall goal is to improve our understanding of the molecular and cell biology of NF1 with the understanding that advances will have important implications for the treatment of these disorders as well as more wide spread understanding of neuroscience, cancer, and development.

描述（由申请人提供）：我们要求为下一次会议提供资金， 国际NF 1和NF 2分子生物学联合会 2001年5月20日至23日在科罗拉多白杨的杰罗姆酒店举行。下 国家神经纤维瘤病基金会（NNFF）， 联合会每年举行会议， 整合细胞生物学家、分子生物学家的努力， 临床医生以前的会议导致了NF 1的鉴定和克隆 和NF 2基因;并促进了对它们的结构和功能的理解。 自1995年以来，每年的会议在更大的开放形式之间交替进行， 该公告是广泛的，包括邀请提交 摘要由NF研究人员在世界各地和更有限的格式， 邀请具体的参与者和讨论者参加。这 后一种形式提供了更多的讨论机会， 未来的战略计划。今年，我们建议引进专家 从外部NF领域来评估当前NF研究。这些将包括 信号传导、肿瘤发生、细胞质组织、 和其他领域。每次会议将由一名NF研究人员和一名 外部专家，其职能不仅是提出一个研究报告， 同时也协助指导讨论和评估NF中的工作， 它涉及每个领域中的现有技术方法。选择受邀者 发言人已作出努力，包括所有相关领域的NF 研究重点是最近的进展。在六场会议中，将有4名发言人 允许25分钟的介绍和额外的20分钟， 讨论最后，“专家联合主席”将被要求在 更大的背景下。确保青年的参与 研究员，每名参与者将与一名初级成员一起被邀请 他们的实验室（研究生或博士后）。我们预计这一 有机会激发年轻科学家从事NF研究的兴趣 （特别是那些为专家联合主席实验室而来的人）。我们预计 这一形式将强调新的突破，并有助于确定 目前的方法和/或理解存在重大差距。总的目标是 为了提高我们对NF 1的分子和细胞生物学的理解， 了解这些进展将对治疗产生重要影响， 以及对神经科学更广泛的了解， 癌症和发育