NNFF Intl Consortium--Molecular Biology of NF1 and NF2

NNFF国际联盟--NF1和NF2的分子生物学

• 批准号: 6359781
• 负责人: Luis Fernando Parada
• 金额: $ 6.85万
• 依托单位: CHILDREN'S TUMOR FOUNDATION
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-04-15 至 2002-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6359781
• 关键词: international health /scientific organization; meeting /conference /symposium; molecular biology; neurofibromatosis; neurofibromatosis type 1 protein /gene; travel

DESCRIPTION (provided by applicant): We request funding for the next meeting of the International Consortium for the Molecular Biology of NF 1 and NF2 to be held May 20-23, 2001 at the hotel Jerome in Aspen Colorado. Under the organization of the National Neurofibromatosis Foundation (NNFF), these Consortium meetings have been held on a yearly basis and have served to consolidate the efforts of cell biologists, molecular biologists, and clinicians. Previous meetings led to the identification and cloning of the NF1 and NF2 genes; and facilitated understanding of their structure and function. Since 1995, the yearly meeting has alternated between a larger open format for which announcement is widespread and includes invitation for submission of abstracts by NF researchers throughout the world and a more limited format, in which specific participants and discussants are invited to participate. This latter format provides opportunity for increased discussion and focussing of strategic plans for the future. This year, we propose to bring in specialists from outside the NF field to evaluate current NF research. These will include leading experts in signal transduction, tumorigenesis, cytoplasm organization, and other areas. Each session will be co-chaired by an NF researcher and an outside specialist whose function will be not only to present a research talk but also to assist in guiding the discussion and evaluating the work in NF as it relates to state of the art approaches in each field. Selection of invited speakers has been made with an effort to include all pertinent areas of NF research with emphasis on recent advances. In six sessions, 4 speakers will be allowed 25 minutes for presentation and an additional 20 minutes for discussion. At the end, the "expert co-chair" will be asked to summarize in the context of the larger picture. To ensure the participation of young investigators, each participant will be invited together with one junior member of their laboratory (graduate student or postdoctoral fellow). We expect this opportunity to stimulate the interest of young scientists to pursue NF research (particularly those coming for the expert co-chair laboratories). We anticipate that this format will emphasize new breakthroughs and serve to identify of critical gaps in current approaches and/or understanding. The overall goal is to improve our understanding of the molecular and cell biology of NF1 with the understanding that advances will have important implications for the treatment of these disorders as well as more wide spread understanding of neuroscience, cancer, and development.

描述(由申请人提供)：我们申请下一次会议的资金 NF1和NF2分子生物学国际联合会即将成立 2001年5月20日至23日在科罗拉多州阿斯彭的杰罗姆酒店举行。在.之下 国家神经纤维瘤病基金会(NNFF)组织，这些 财团会议每年举行一次，并起到了 整合细胞生物学家、分子生物学家和 临床医生。之前的会议导致了NF1的鉴定和克隆 和NF2基因；并促进了对其结构和功能的了解。 自1995年以来，年度会议在更大的开放形式之间交替举行 哪项公告广为流传，并包括邀请提交 世界各地核研究人员的摘要和更有限的格式，在 邀请哪些具体的参与者和讨论者参加。这 后一种格式提供了增加讨论和集中讨论的机会 未来的战略规划。今年，我们建议引进专家 从核素领域之外对当前核素研究进行评价。这些措施包括 信号转导、肿瘤发生、细胞质组织方面的顶尖专家， 以及其他领域。每一次会议将由一名核研究人员和一名 外部专家，其职能将不仅仅是介绍研究演讲 还协助指导讨论和评估核准部的工作 它涉及到每个领域的最新方法。特邀嘉宾评选 演讲者已经努力包括了核问题的所有相关领域 强调最新进展的研究。在六次会议中，将有4位演讲者 允许25分钟用于演示，另外20分钟用于 讨论。最后，将请“专家共同主席”在 更大图景的背景。确保年轻人的参与 调查人员，每个参与者将被邀请与一名初级成员一起被邀请 他们的实验室(研究生或博士后)。我们预料到了这一点 激发青年科学家从事核素研究的机会 (特别是那些来参加专家联合主席实验室的人)。我们期待着 这种形式将强调新的突破，并有助于识别 当前方法和/或理解中的严重差距。总体目标是 为了提高我们对NF1分子和细胞生物学的理解 理解这一进展将对治疗产生重要影响 以及对神经科学更广泛的理解， 癌症和发育。