CORNEAL TOPOGRAPHY ANALYSIS TOOL

俄亥俄州州立大学开发了一种定量研究工具 为了使输出标准化并提供一致的 各种角膜地形图分析。 该工具已被证明 在实验室中有效地转换角膜的地形数据 从不同的地形到单一的格式。 这使得 研究人员将比较取自同一角膜的地形图数据 不同的地形机器。 拟议研究的主要目标 是在FDA设计控制范围内开发该器械的临床版本 基于这个实验室模型，可通过网络访问。 这样做的目的是 研究将包括将现有的实验室软件整合到 一个参数化的自动化软件包;开发一个接口来访问 万维网;以及开发独立于机器的 圆锥角膜进展与屈光手术地形图分析 结果。 基于网络的商业化模式将允许最大的 灵活地使用该装置， 目前使用的系统。 此外，该设备还将为用户提供 由于目前没有一种独特的地形分析选项， 以及扩展其特定机器的有用性。 拟定商业应用： 应用研究将使临床医生，公司和其他眼科医生 专业人员的能力，以标准化的地形分析，其 患者的眼睛。 目前，这些地图还没有广泛使用的标准， 因为每个制造商都使用独特的色标来显示地形 在他们自己的机器上成像的地图。 这使得病人的共同管理 如果临床医生没有相同的机器或不习惯 查看对方的输出地图 这个问题再次出现，如果 患者将从其执业临床医生处迁出。 与 所提出的角膜地形图工具，患者的数据将是普遍的 可读性和可访问性。 拟议的设备将允许临床医生 产生圆锥角膜和折射地形图指数， 在他们现有的机器上。 这将提高临床实用性 由于用户将不会受到限制， 他们的机器的局限性或购买新机器的成本。 最后， 该装置可用于改进LASIK手术的消融算法 通过允许临床医生对大型数据集进行错误分析， LASIK术后结果。

A quantitative research tool has been developed at The Ohio State University for the expressed purpose of standardizing output and providing consistent analysis from a variety of Corneal Topographers. This tool has been proven in the laboratory to effectively convert the topographic data of the cornea from different topographers to a single format. This has allowed researchers to compare topographic data of the same cornea taken from varying topographic machines. The main objective of the proposed research is to develop, within FDA design controls, a clinical version of the device based on this laboratory model, accessible via the web. The aims of this research will encompass consolidating the existing laboratory software into a parameterized automated package; developing an interface to access the World Wide Web; and development of machine independent modules for the analysis of keratoconus progression and refractive surgery topographic outcomes. The web-based commercialization model will allow the greatest flexibility for use of the device with the various topographer operating systems currently in use. In addition, the device will provide the user with a unique slate of topography analysis options not currently available, as well as extend the usefulness of their specific machine. PROPOSED COMMERCIAL APPLICATION: The applied research will allow clinicians, companies and other ophthalmic professionals the ability to standardize the topographical analysis of their patients' eyes. Currently there is no widely used standard for these maps, as each manufacturer uses a unique color scale to display the topographic maps imaged on their own machines. This makes co-management of patients difficult if the clinicians do not have the same machine or are not used to viewing the other's output maps. This difficulty arises again if the patient were to move residence away from their practicing clinician. With the proposed corneal topography tool, a patient's data would be universally readable and accessible. The proposed device will allow clinicians to generate keratoconic and refractive topographic indices that are not inherent on their current machine. This will enhance the clinical utility of current topographers since users will not be constrained by the limitations of their machines or the costs of buying a new one. Finally, the device could be used to improve ablation algorithms for LASIK procedures by allowing clinicians to perform error analyses on large datasets of post-ablation LASIK outcomes.