CORNEAL TOPOGRAPHY ANALYSIS TOOL

俄亥俄州立大学开发了一种定量研究工具 为了明确的目的，使产出标准化并提供一致的 来自各种角膜地形图的分析。这个工具已经过了验证 在实验室中有效地转换角膜的地形图数据 从不同的地形师到单一的格式。这使得 研究人员将同一角膜的地形数据进行比较 不同地形的机器。拟议研究的主要目标 是在FDA的设计控制下开发该设备的临床版本 基于此实验室模型，可通过网络访问。这样做的目的是 研究将包括将现有的实验室软件整合到 一个参数化的自动化包；开发一个接口来访问 万维网；以及开发与机器无关的模块 圆锥角膜进展与屈光手术地形图分析 结果。基于网络的商业化模式将允许最大的 在各种地形图操作员的情况下灵活使用设备 目前正在使用的系统。此外，该设备将为用户提供 由于一系列独特的地形分析选项当前不可用， 以及扩展其特定机器的有用性。 建议的商业应用： 这项应用研究将使临床医生、公司和其他眼科医生 专业人员标准化其地形分析的能力 病人的眼睛。目前这些地图还没有广泛使用的标准， 因为每个制造商都使用唯一的色标来显示地形 地图在他们自己的机器上成像。这使得对患者的共同管理 如果临床医生没有相同的机器或不习惯 查看对方的输出映射。这一困难再次出现，如果 患者将搬离他们执业的临床医生的住所。使用 所提出的角膜地形图工具，患者的数据将是通用的 可读性和可访问性。拟议中的设备将允许临床医生 生成的角锥和折射地形指数不是 在他们目前的机器上是固有的。这将提高临床实用价值。 ，因为用户将不受 他们的机器的局限性或购买新机器的成本。最后， 该装置可用于改进LASIK手术的消融算法 通过允许临床医生对大数据集执行错误分析 准分子激光原位角膜磨镶术后结果。

A quantitative research tool has been developed at The Ohio State University for the expressed purpose of standardizing output and providing consistent analysis from a variety of Corneal Topographers. This tool has been proven in the laboratory to effectively convert the topographic data of the cornea from different topographers to a single format. This has allowed researchers to compare topographic data of the same cornea taken from varying topographic machines. The main objective of the proposed research is to develop, within FDA design controls, a clinical version of the device based on this laboratory model, accessible via the web. The aims of this research will encompass consolidating the existing laboratory software into a parameterized automated package; developing an interface to access the World Wide Web; and development of machine independent modules for the analysis of keratoconus progression and refractive surgery topographic outcomes. The web-based commercialization model will allow the greatest flexibility for use of the device with the various topographer operating systems currently in use. In addition, the device will provide the user with a unique slate of topography analysis options not currently available, as well as extend the usefulness of their specific machine. PROPOSED COMMERCIAL APPLICATION: The applied research will allow clinicians, companies and other ophthalmic professionals the ability to standardize the topographical analysis of their patients' eyes. Currently there is no widely used standard for these maps, as each manufacturer uses a unique color scale to display the topographic maps imaged on their own machines. This makes co-management of patients difficult if the clinicians do not have the same machine or are not used to viewing the other's output maps. This difficulty arises again if the patient were to move residence away from their practicing clinician. With the proposed corneal topography tool, a patient's data would be universally readable and accessible. The proposed device will allow clinicians to generate keratoconic and refractive topographic indices that are not inherent on their current machine. This will enhance the clinical utility of current topographers since users will not be constrained by the limitations of their machines or the costs of buying a new one. Finally, the device could be used to improve ablation algorithms for LASIK procedures by allowing clinicians to perform error analyses on large datasets of post-ablation LASIK outcomes.