HIGH RESOLUTION X-RAY FLUORESCENCE DETECTOR
HIGH RESOLUTION X-RAY FLUORESCENCE DETECTOR
批准号:
6293934
负责人:
Ke Zhang
金额:
$10.08万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2001
资助国家:
美国
项目状态:
已结题
起止时间:
2001-03-02 至 2002-08-31
中文摘要
描述(来自申请人摘要的逐字记录):已证明
多层分析器阵列检测器在X射线荧光中是有利的
在高通量和稀金属条件下进行检测。用一个好的拒绝
速率,约25倍,以及合理的大立体角,亚毫摩尔
浓度可以常规获取。然而,
探测器仍然落后于光子通量,亮度增加,
第三代甚至第四代同步辐射源。有超过100至
在第三代源处,通量增加1000,这些源将允许
检测金属浓度为10微摩尔或几ppm
范围这将允许监测一些生物相关的金属,
vivo.因此,我们建议开发X射线荧光检测器,
多层对带初级和次级两级抑制
多层,预计拒收率将超过200次。
在20%的吞吐量下,有效计数率的预期增益
在稀释系统中可高达40倍。初步评估显示,
探测器可以在宽的能量范围内调谐,并覆盖大的固体
角度第一阶段项目的主要目标是设计和制造一个
原型多层对探测器。探测器的测试与评价
性能将有助于多层对分析器阵列的设计
检测器二期工程将把这种探测器研制成产品。
拟定商业应用:
对非常灵敏和高计数率的X射线荧光检测器的需要是很好的
正当的 该仪器将是至关重要的x射线光谱和显微荧光
在高通量和稀释情况下对生物系统成像。 随着日益增长的
光子通量在新的同步辐射光源,探测器将有更好的市场
比荧光电离室和固态探测器,
目前可用。
英文摘要
DESCRIPTION (Verbatim from the Applicant's Abstract): It has been demonstrated
that multilayer analyzer array detector is advantageous in x-ray fluorescence
detection under high flux and dilute metal conditions. With a good rejection
rate, about 25 times, and reasonably large solid angle, sub-millimolar
concentration can be routinely accessed. However, the performance of the
detector is still lagging behind the photon flux and brightness increases at
the third or even fourth generation synchrotron sources. With more than 100 to
1000 flux increases at the third generation source, these sources would permit
detection of metal concentration in the order of 10 micro-Molar or several ppm
range. This will allow the monitoring of some biologically relevant metals in
vivo. Thus we propose to develop x-ray fluorescence detector using synthetic
multilayer pairs. With two-stage rejection of primary and secondary
multilayers, it is anticipated that the rejection rate will exceed 200 times.
With a 20 percent throughput, the anticipated gain on the effective count rate
can be as high as 40 times on dilute systems. Initial evaluation shows that the
detector can be made tunable in a wide energy region and to cover a large solid
angle. The major goal for the Phase I project is to design and fabricate a
prototype multilayer pair detector. The test and evaluation of the detector
performance will aid in the design of a multilayer pair analyzer array
detector. Phase II project will develop such a detector to a product.
PROPOSED COMMERCIAL APPLICATION:
The need for a very sensitive and high count rate x-ray fluorescence detector is well
justified. The instrument will be vital to x-ray spectroscopy and micro fluorescence
imaging on biological systems under high flux and dilute situations. With ever increasing
photon flux at the new synchrotron sources, the detector will have a better market
potential than fluorescence ionization chambers and the solid state detectors which are
currently available.
期刊论文(0)
专著(0)
科研奖励(0)
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