CLINICAL TRIALS OF ANTIFUNGAL THERAPIES

本合同的目的是提供临床试验 协作小组接触适当的高危人群， 提供专业知识，以构建和实施受控临床 试验解决了严重真菌病的关键管理问题。 该小组将由一个协调机构进行协调和评价。 预计该小组将： 1)根据公共卫生优先次序制定科学议程 需要NIAID批准; 2)为患者护理和相关成本提供可靠的行业支持， 拟进行的审判; 3)提供行政数据管理和统计支持， 试验的制定、实施和分析; 4)提供工地监察及数据和安全质素保证;及 5)评估和报告进展和结果，包括摘要和 独立数据和安全性监查委员会要求的分析 以及所有研究的安全性。

The objective of this contract is to provide a clinical trial collaborative group accessing the appropriate at-risk populations and providing the expertise to construct and conduct controlled clinical trials addressed the key management problems in serious fungal diseases. The group will be coordinated and evaluated by a coordinating institution. It is expected that the group will: 1) Formulates scientific agenda prioritized according to public health needs for approval by the NIAID; 2) Secure industrial support for patient care and related costs to enable the proposed trials to run to completion; 3) Provide administrative data management and statistical support for development, implementation and analysis of the trials; 4) Provide site monitoring and data and safety quality assurance; and 5) Assess and report progress and results, including summaries and analyses as required by an independent Data and Safety Monitoring Board and for the safety of all studies.