Does vitamin D supplementation reduce mortality for older adults?: a pilot trial

研究表明，维生素D含量低的人患某些慢性疾病和过早死亡的风险可能会增加。这促使人们呼吁在全民范围内补充维生素D，尽管没有来自临床试验的有力证据。在2008年一份具有里程碑意义的报告中，国际癌症研究机构呼吁对高剂量维生素D补充剂进行随机试验。我们计划进行试点，为大规模化学预防试验的实施提供参考。

Studies suggest that people with low vitamin D may have increased risks of some chronic diseases and early death. This has prompted calls to introduce population-wide vitamin D supplementation, although there is no good evidence from clinical trials. In a landmark 2008 report, the International Agency for Research on Cancer called for randomised trials of high-dose vitamin D supplementation. We plan to pilot such a trial, to inform implementation of a large-scale chemoprevention trial.