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CORE--PEPTIDE SYNTHESIS, PURIFICATION, FOLDING AND STRUCTURAL ANALYSIS FACILITY

CORE--PEPTIDE SYNTHESIS, PURIFICATION, FOLDING AND STRUCTURAL ANALYSIS FACILITY
核心——肽合成、纯化、折叠和结构分析设备
批准号：
6340689
负责人：
ALAN J WARING
金额：
$15.97万
依托单位：
UNIVERSITY OF CALIFORNIA LOS ANGELES
依托单位国家：
美国
项目类别：
财政年份：
2000
资助国家：
美国
项目状态：
已结题
起止时间：
2000-09-01 至 2001-08-31
来源：
https://reporter.nih.gov/project-details/6340689
关键词：
antibiotics biomedical facility chemical registry /resource drug design /synthesis /production peptide chemical synthesis peptides protein folding protein purification protein structure function

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Core is responsible for preparing the various peptides. Protegrins will generally be synthesized by Dr. Waring at the UCLA site. LL-37 and related alpha-helical peptides will be synthesized by Dr. Pohl at Emory, as will any protegrins that would be benefit from t-boc synthesis. The availability of high-quality peptides is absolutely essential for the proposed studies. Dr. Waring and Pohl are highly accomplished investigators with access to state-of-the-art tools for peptide synthesis, purification and characterization.
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Integrated, Modular Equipment for Large-scale and Small-scale Peptide Synthesis
Development of Retrocyclin Microbicides
CORE--PEPTIDE SYNTHESIS, PURIFICATION, FOLDING AND STRUCTURAL ANALYSIS FACILITY
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