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GENETICS OF SLE IN MULTIPLEX FAMILIES

GENETICS OF SLE IN MULTIPLEX FAMILIES
多重家族中系统性红斑狼疮的遗传学
批准号：
6303732
负责人：
CHAIM O. JACOB
金额：
$3.56万
依托单位：
UNIVERSITY OF SOUTHERN CALIFORNIA
依托单位国家：
美国
项目类别：
财政年份：
1999
资助国家：
美国
项目状态：
已结题
起止时间：
1999-12-01 至 2000-11-30
来源：
https://reporter.nih.gov/project-details/6303732
关键词：
clinical research connective tissue disorder diagnosis family genetics genetic disorder diagnosis human subject linkage mapping polymerase chain reaction systemic lupus erythematosus

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中文摘要
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英文摘要
The purpose of this study is to identify genes in the pathogenesis of human SLE using two basic approaches: a candidate gene approach and a genome-wide search in families in which two or more relatives have SLE. We are developing a genetic linkage map for systemic lupus erythematosis (SLE) on PCR - detectable markers (mcorsatellite repeats).
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