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REPEATED DOSES OF LPJ-394 IN PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS

REPEATED DOSES OF LPJ-394 IN PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS
系统性红斑狼疮患者重复服用 LPJ-394
批准号：
6305475
负责人：
STANLEY BALLOU
金额：
$1.92万
依托单位：
CASE WESTERN RESERVE UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
1999
资助国家：
美国
项目状态：
已结题
起止时间：
1999-12-01 至 2000-11-30
来源：
https://reporter.nih.gov/project-details/6305475
关键词：
antinuclear autoantibody chemical conjugate clinical research drug administration rate /duration drug screening /evaluation human subject human therapy evaluation longitudinal human study placebos systemic lupus erythematosus

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中文摘要
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英文摘要
This is a prospective multi-center double-blind, placebo-controlled Phase II-III trial in which an investigational new drug, LPJ 394, will be tested for its ability to reduce the production of antibodies to double stranded DNA (anti-dsDNA) and limit flare-ups of active renal disease in patients with lupus nephritis. The subjects will receive medication for 52 weeks, after which there will be a six month period of follow-up to assess clinical lupus activity, anti-DNA levels and health status.
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REPEATED DOSES OF LPJ-394 IN PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS
  • 批准号：
    6115351
  • 项目类别：
  • 资助金额：
    $1.92万
  • 财政年份：
    1998
  • 负责人：
    STANLEY BALLOU
  • 依托单位：
    CASE WESTERN RESERVE UNIVERSITY
REPEATED DOSES OF LPJ-394 IN PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS
  • 批准号：
    6276585
  • 项目类别：
  • 资助金额：
    $1.83万
  • 财政年份：
    1997
  • 负责人：
    STANLEY BALLOU
  • 依托单位：
    CASE WESTERN RESERVE UNIVERSITY