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HIGHLY ACTIVE ANTIRETROVIRAL THERAPY W/WO RHIL 2 FOR HIV POSITIVE PATIENTS

HIGHLY ACTIVE ANTIRETROVIRAL THERAPY W/WO RHIL 2 FOR HIV POSITIVE PATIENTS
针对 HIV 阳性患者的高活性抗逆转录病毒治疗（含 RHIL 2）
批准号：
6305290
负责人：
RICHARD B POLLARD
金额：
$3.42万
依托单位：
UNIVERSITY OF TEXAS MED BR GALVESTON
依托单位国家：
美国
项目类别：
财政年份：
1999
资助国家：
美国
项目状态：
已结题
起止时间：
1999-12-01 至 2000-11-30
来源：
https://reporter.nih.gov/project-details/6305290
关键词：
AIDS therapy HIV infections antiAIDS agent clinical research clinical trial phase I combination chemotherapy drug administration routes drug resistance drug screening /evaluation human subject human therapy evaluation immunotherapy interleukin 2 intravenous administration phenotype quality of life virus load virus replication

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中文摘要
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英文摘要
The purpose of this research study is to determine the safety, tolerance and effectiveness of Interleukin-2 (IL-2) in combination with highly active antiretroviral therapy (HAART), drugs that fight HIV, compared to HAART alone and to determine the best route of giving IL-2 in combination with this antiretroviral therapy. HAART is being given for its effectiveness to fight HIV infection and consists of one of the four combinations of drugs plus indinavir: ZDV + 3tc; ZDV+ddI; d4T+3TC; or d4T+ddI. IL-2 is an important substance which is naturally produced by the body's CD4 cells. People with HIV do not produce enough IL-2. IL-2 is being tested to see if it will increase the number of CD4 cells and boost the immune system.
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NORTH-CENTRAL CALIFORNIA-CENTER FOR AIDS RESEARCH
  • 批准号：
    7562184
  • 项目类别：
  • 资助金额：
    $13.97万
  • 财政年份：
    2007
  • 负责人：
    RICHARD B POLLARD
  • 依托单位：
    UNIVERSITY OF CALIFORNIA AT DAVIS
NORTH-CENTRAL CALIFORNIA-CENTER FOR AIDS RESEARCH
  • 批准号：
    7349680
  • 项目类别：
  • 资助金额：
    $3.91万
  • 财政年份：
    2006
  • 负责人：
    RICHARD B POLLARD
  • 依托单位：
    UNIVERSITY OF CALIFORNIA AT DAVIS
NORTH-CENTRAL CALIFORNIA-CENTER FOR AIDS RESEARCH
  • 批准号：
    7165486
  • 项目类别：
  • 资助金额：
    $25.25万
  • 财政年份：
    2005
  • 负责人：
    RICHARD B POLLARD
  • 依托单位：
    UNIVERSITY OF CALIFORNIA AT DAVIS
NORTH-CENTRAL CALIFORNIA-CENTER FOR AIDS RESEARCH
  • 批准号：
    6971489
  • 项目类别：
  • 资助金额：
    $42.47万
  • 财政年份：
    2004
  • 负责人：
    RICHARD B POLLARD
  • 依托单位：
    UNIVERSITY OF CALIFORNIA AT DAVIS
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