课题基金 / 基金详情

SECOND GENERATION TOOLS FOR FUNCTIONAL GENOMICS

SECOND GENERATION TOOLS FOR FUNCTIONAL GENOMICS
第二代功能基因组学工具
批准号:
6298635
负责人:
Stephen G Chamberlin
金额:
$36.82万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
1999
资助国家:
美国
项目状态:
已结题
起止时间:
1999-09-01 至 2003-05-31

项目摘要

项目成果

Stephen G Chamberlin的其他基金

相关文献

中文摘要
翻译
申请人?描述:EraGen将开发一款新的功能基因组软件
英文摘要
APPLICANT?S DESCRIPTION: EraGen will develop a new functional genomics software suite that helps scientists use genomic sequence data to solve biological and biomedical problems in this Phase II period. The product will take the scientist beyond classical approaches to sequence annotation, which use BLAST searches to identify homologs, and assume that two proteins related by common ancestry must have analogous functions. The Phase I period demonstrated that this approach to database annotation is often misleading, and frequently misses meaningful interpretations in metazoan proteins. The Phase II period will refine and fully develop the software initiated in Phase I. This software will serve to identify where function might have changed during divergence of a sequence family, and also where recruitment of function has occurred using rates of change from the DNA sequence. In addition, the tools to exploit probabilistic ancestral sequences for both protein/protein and DNA/protein alignments will be fully developed. These tools will detect distant homologs, identify errors across sequence databases, and augment current approaches to gene finding. PROPOSED COMMERCIAL APPLICATIONS: Not Available
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会议论文
Biochemical and pharmacological studies of human membrane progesterone receptors
An Expanded Genetic Information System
  • 批准号:
    6626075
  • 项目类别:
  • 资助金额:
    $25.0万
  • 财政年份:
    2001
  • 负责人:
    Stephen G Chamberlin
  • 依托单位:
SOFTWARE FOR EVOLUTION BASED FUNCTIONAL GENOMICS
  • 批准号:
    6014957
  • 项目类别:
  • 资助金额:
    $1.84万
  • 财政年份:
    1999
  • 负责人:
    Stephen G Chamberlin
  • 依托单位:
SECOND GENERATION TOOLS FOR FUNCTIONAL GENOMICS
  • 批准号:
    6536469
  • 项目类别:
  • 资助金额:
    $34.87万
  • 财政年份:
    1999
  • 负责人:
    Stephen G Chamberlin
  • 依托单位: