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CORE--CELL AND ANIMAL MODEL

CORE--CELL AND ANIMAL MODEL
核心--细胞和动物模型
批准号：
6284079
负责人：
RANDALL H KRAMER
金额：
$6.07万
依托单位：
UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
依托单位国家：
美国
项目类别：
财政年份：
2001
资助国家：
美国
项目状态：
已结题
起止时间：
2001-06-01 至 2005-11-30
来源：
https://reporter.nih.gov/project-details/6284079
关键词：
biomedical facility cell line disease /disorder model keratinocyte laboratory mouse mouth neoplasms neoplastic growth squamous cell carcinoma tissue /cell culture transfection

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英文摘要
Important parts of several of the individually proposed research programs of this Program Project depend on the use of human oral squamous cell carcinoma cells and animal models for oral cancer development and progression. The Cell and Animal Model Core will provide the material required for these studies. Both malignant and normal keratinocyte cell lines, which are essential tools for the proposed studies are available. In addition, Core B will assist in the transfection of cells using retroviral vectors and in the performance of tumor invasion and migration assays. Another important task of the Core Facility will to make available several different animal models of oral cancer for the study of development, progression and invasion/metastasis.
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