LOS ANGELES HIV PREVENTION TRIALS UNIT

这项申请将在洛杉矶县建立一个艾滋病毒预防试验联盟(HPTC)，它将是NIH艾滋病毒预防试验网络(HPTN)下的一个单位，并将与其密切合作。洛杉矶HPTC将为HPTN带来以下四个群体之间强大的本地合作伙伴关系：1)能够为历史上服务不足的社区的预防研究建立支持的社区倡导者和教育工作者2)具有高危人群工作经验的社区研究人员和流行病学家3)能够设计并迅速实施第一、第二和第三阶段行为和治疗预防及杀微生物剂试验的行为科学家和临床医生，以及4)致力于确定和测量针对艾滋病毒的保护性免疫的关键相关的基本病毒学家和免疫学家。洛杉矶HPTC汇集了社区利益相关者和倡导者、来自四个学术机构(南加州大学、加州大学洛杉矶分校、加州州立大学、长滩大学和查尔斯·R·德鲁医学与科学大学)的研究人员、服务于非裔美国人和拉丁裔以及洛杉矶同性恋和双性恋社区的社区护理和预防团体(以帮助所有人(T.H.)诊所、AltaMed和同性恋中心)和艾滋病毒流行病学和预防研究的专家。该联盟的目标是为促进对有效的行为、杀菌和治疗干预措施的理解做出重大贡献，这些干预措施将减少艾滋病毒的传播，同时建立社区对预防研究的支持。

This application will establish in Los Angeles County a HIV Prevention Trials Consortium (HPTC) that will be a unit under and will work in close collaboration with the NIH HIV Prevention Trials Network (HPTN). The Los Angeles HPTC will bring to the HPTN a strong local partnership between the following four groups: 1) community advocates and educators who can build support for prevention research in historically underserved communities 2) community-based researchers and epidemiologists with experience working with high-risk populations 3) behavioral scientists and clinicians capable of designing and rapidly implementing Phase I, II and III behavioral and therapeutic prevention and microbicide trials, and, 4) basic virologists and immunologists committed to identifying and measuring the key correlates of protective immunity against HIV. The Los Angeles HPTC has been formed by bringing together community stakeholders and advocates, researchers from four academic institutions (University of Southern California, University of California at Los Angeles, California State University, Long Beach and the Charles R. Drew University of Medicine and Sciences), community-based care and prevention groups serving the African American and Latino, and gay and bisexual communities of Los Angeles (To Help Everyone (T.H.E.) Clinic, AltaMed, and the Gay and Lesbian Center) and experts in HIV epidemiology and prevention research. The goal of this consortium is to make significant contributions to advancing the understanding of effective behavioral, microbicidal and therapeutic interventions that will reduce HIV transmission while building community support for prevention research.