Supplementary support for the research programme funded by the CI Grant ST/G008248/1, FELIS( Free Electron Laser integration for SNOM) project.

对 CI Grant ST/G008248/1 资助的研究项目 FELIS（SNOM 自由电子激光集成）项目的补充支持。

• 批准号: ST/K00154X/1
• 负责人: Swapan Chattopadhyay
• 金额: $ 3.36万
• 依托单位: University of Liverpool
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2012
• 资助国家: 英国
• 起止时间: 2012 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=ST%2FK00154X%2F1
• 关键词: Supplementary; support; research; programme; funded

Oesophageal cancer is the fastest rising incidence of cancer in the western world. It is particularly difficult to diagnose with the result that by the time most patients visit their doctor with symptoms the cancer has spread and it is difficult to treat successfully by surgery. However there is a pre-existing benign condition called Barret's oesophagus which can be monitored by gastrointestinal endoscopy. A small percentage of patients with Barrett's oesophagus will develop oesophageal cancer. If these patients can be identified early then it is possible to treat them successfully. This research will install a high performance microscope called a SNOM on the infrared free electron laser on the ALICE accelerator at Daresbury. This microscope will make it possible to obtain high resolution chemical images of tissue from patients with Barrett's oesophagus that will make it possible to diagnose whether the patients will go on to develop oesophageal cancer.

食管癌是西方世界发病率上升最快的癌症。这是特别困难的诊断结果，大多数病人去看医生的时候，症状的癌症已经扩散，很难通过手术成功治疗。然而，有一种预先存在的良性疾病称为巴雷特食管，可以通过胃肠道内窥镜检查进行监测。一小部分巴雷特食管患者会发展为食管癌。如果这些患者能够及早发现，那么就有可能成功治疗他们。这项研究将在达雷斯伯里的ALICE加速器上的红外自由电子激光器上安装一台名为SNOM的高性能显微镜。这种显微镜将使人们有可能获得高分辨率的化学图像的组织从患者巴雷特食管，这将使人们有可能诊断是否患者将继续发展食管癌。