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CEREBROSPINAL FLUID MARKERS OF AGING AND BRAIN DISEASE

CEREBROSPINAL FLUID MARKERS OF AGING AND BRAIN DISEASE
衰老和脑部疾病的脑脊液标志物
批准号:
6413958
负责人:
Stanley I. Rapoport
金额:
$0.0万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
--
资助国家:
美国
项目状态:
未结题
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英文摘要
Tau protein is was found to be elevated in the cerebrospinal fluid (CSF) of patients with Alzheimer disease (AD), reflecting neurofibrillary tangle formation. CSF tau concentrations, when combined with age in a discriminant function analysis, increased the power to maker a correct diagnosis of AD in subjects less than 70 years old. Interleukin 6 (IL-6) contributes to the interaction between immune mechanisms and brain. CSF concentrations from geriatric patients with major depression showed significantly reduced levels of both IL-6 and the soluble Il-6 receptor (sIL-6R), measured by enzyme-linked immunosorbant assays (ELISA), compared with control CSF.
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IMAGING DECREASED BRAIN DOCOSAHEXAENOIC ACID METABOLISM AND SIGNALING
  • 批准号:
    8361447
  • 项目类别:
  • 资助金额:
    $0.81万
  • 财政年份:
    2011
  • 负责人:
    Stanley I. Rapoport
  • 依托单位:
DOWN SYNDROME, NEURODEVELOPMENT & NEURODEGENERATION
  • 批准号:
    6434775
  • 项目类别:
  • 资助金额:
    $0.0万
  • 财政年份:
    --
  • 负责人:
    Stanley I. Rapoport
  • 依托单位:
Mechanisms Of Action: Lithium And Other Antimanic Drugs
  • 批准号:
    6521733
  • 项目类别:
  • 资助金额:
    $0.0万
  • 财政年份:
    --
  • 负责人:
    Stanley I. Rapoport
  • 依托单位:
Cerebrospinal Fluid Markers Of Aging And Brain Disease
  • 批准号:
    6667885
  • 项目类别:
  • 资助金额:
    $0.0万
  • 财政年份:
    --
  • 负责人:
    Stanley I. Rapoport
  • 依托单位:
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