MINIMIZATION OF PROTEIN & CELLULAR ADHESION BY COPOLYMER & METAL OXIDE GRAFT

尽量减少蛋白质摄入

• 批准号: 6345040
• 负责人: KEVIN HEALY
• 金额: $ 5.15万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-09-01 至 2001-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6345040
• 关键词: bioengineering /biomedical engineering; biological products; biomaterials; biomedical resource; genetics; health care; proteins; statistics /biometry; technology /technique

A novel interpentrating copolymer of acrylamide and ethylene glycol has been designed to minimize biological interactions such as protein adsorption and cellular adhesion on implants. ESCA has been used to characterize the elemental composition of the copolymer and determine under what experimental conditions the interpentrating network is formed. Further work with imaging ToF SIMS has been done to investigate the surface composition of patterned surfaces designed with non-adhesive acrylamide-ethylene glycol copolymer regions and cell-adhesive regions.

一种新型丙烯酰胺与乙烯的互穿共聚物