CORE--ANIMAL

核心--动物

• 批准号: 6338880
• 负责人: JEANNE M WALLACE
• 金额: $ 19.92万
• 依托单位: WAKE FOREST UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-07-01 至 2001-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6338880
• 关键词: Cercopithecidae; animal colony; atherosclerosis; biomedical facility; blood lipoprotein metabolism; laboratory mouse

The primary objectives of the Animal Core are as follows: 1. Provide veterinary care for the monkeys and mice of the Program Project. 2. Provide veterinary and technical support for liver biopsy surgeries and for associated postoperative care. 3. Provide technical support for collection of blood samples, blood pressures, body weights, administering isotopes and performing urine sample collection, and preparing data sheets. 4. Coordinate and supervise the diet laboratory and animal care staffs to assure that diets are prepared and fed according to protocol. 5. Insure that liver perfusion studies and necropsies are performed according to protocol. 6. Evaluate atherosclerosis extent and severity in the aorta, coronary, carotid and iliac arteries. 7. Provide technical support for the transgenic mouse breeding colony.

动物核心的主要目标如下： 1。为程序的猴子和老鼠提供兽医护理 项目。 2。为肝活检手术提供兽医和技术支持 用于相关的术后护理。 3。为收集血液样本，血液提供技术支持 压力，体重，施用同位素和执行尿液 示例收集并准备数据表。 4。协调和监督饮食实验室和动物护理人员 确保根据方案准备和喂食饮食。 5。确保进行肝灌注研究和死灵。 根据协议。 6。评估动脉粥样硬化的程度和主动脉，冠状动脉的严重程度 颈动脉和小动脉。 7。为转基因小鼠育种菌落提供技术支持。